Washington University
Structural ALDH activity of E. histolytica alcohol dehydrogenase 2 analyzed
Published in Law and Health Weekly, January 1st, 2005
"The ADHE family of enzymes are bifunctional acetaldehyde dehydrogenase (ALDH)/alcohol dehydrogenase (ADH) enzymes that probably arose from the fusion of genes encoding separate ALDH and ADH enzymes. Here we have used the Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) enzyme as a prototype to analyze the structure and function of the ALDH domain of ADHE enzymes," wrote M.H. Chena and colleagues, Washington University.
"We find that the N-terminal domain of EhADH2,...
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