University of Texas School of Medicine, Houston
Memory for contextual fear suppressed by entorhinal cortex plasticity
Published in Law and Health Weekly, January 22nd, 2005
"Several studies have delineated a role for the hippocampus in fear conditioning. However, in this task, the role of the EC, the main input-output structure for the hippocampus, is uncertain.
"The extracellular signal-regulated kinase (ERK) cascade has been shown to be a molecular correlate for long-term memory, and its activity is required for various types of memory storage, including fear memory. In this study, we show that ERK activity in the EC increased 90 min after fear conditioning," wrote A.E. Hebert and colleagues,...
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