Published in Law and Health Weekly, March 12th, 2005
"The aggregation of cc-synuclein, involved in the pathogenesis of several neurodegenerative disorders such as Parkinson disease, is enhanced in vitro by biogenic polyamines binding to the highly charged C-terminal region aa109-140," wrote W. Hoyer and colleagues, Max Planck Institute.
"In this study, we investigated the influence of this region on the aggregation kinetics, monitored by thioflavin T binding and static light scattering, and morphology, assessed by electron microscopy, fluorescence microscopy, and turbidity, by comparing...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Law and Health Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.