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Jichi Medical School, Saitama

Gac fruit extract diminishes tumor growth and neovascularization

Published in Law and Health Weekly, May 28th, 2005

Gac fruit extract diminishes tumor growth and neovascularization.

According to recent research from Japan, "the antitumor activity of the crude water extract from Gac fruit (Momordica cochinchinensis) was investigated in vivo and in vitro. A water extract prepared from 0.75 and 0.25 mg dry weight of Gac fruit per gram body weight was given daily to Balb/c mice (n=15/group). The water extract inhibited the growth of the colon 26-20 adenocarcinoma cell line, transplanted in Balb/c mice, reducing wet tumor weight by 23.6%."

"Histological and immunohistochemical results indicated that Gac water extract reduced the density of blood vessels around...

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