Published in Law and Health Weekly, July 9th, 2005
According to recent research published in the journal Gastroenterology, "Cytokines including tumor necrosis factor alpha (TNF-alpha) may create a state of growth hormone (GH) resistance in Crohn's disease. Anabolic effects of GH are mediated via phosphorylation of the signal transducer and activator of transcription (STAT)5b transcription factor."
L.M. Difedele and colleagues, Yale University School of Medicine explained, "Although GH resistance in other settings has been linked to a defect in janus kinase-STAT signaling, the molecular basis for GH resistance in colitis...
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