Yale University School of Medicine
TNF-alpha blockade restores growth hormone signaling in murine colitis
Published in Law and Health Weekly, July 9th, 2005
According to recent research published in the journal Gastroenterology, "Cytokines including tumor necrosis factor alpha (TNF-alpha) may create a state of growth hormone (GH) resistance in Crohn's disease. Anabolic effects of GH are mediated via phosphorylation of the signal transducer and activator of transcription (STAT)5b transcription factor."
L.M. Difedele and colleagues, Yale University School of Medicine explained, "Although GH resistance in other settings has been linked to a defect in janus kinase-STAT signaling, the molecular basis for GH resistance in colitis...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Law and Health Weekly
More Articles from Law and Health Weekly
- Acuity Pharmaceuticals
Deal signed with Intradigm to develop topical drugs for ophthalmic uses - Aphton Corporation
Biotech company appoints Manfred Ruediger as chief operating officer - Avantogen
European patent grant for immune-enhancing adjuvant - European Society for Human Genetics
Geneticists oppose singling out Jewish women in European patent - Exelixis, Inc.
Collaboration to focus on therapeutics for cancer, inflammation, tissue repair - Fred Hutchinson Cancer Research Center, Seattle
Selection during HIV-1 transmission may vary depending on infecting subtype - More from this issue of Law and Health Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
