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University of Toronto

ARBs reduce left ventricular remodeling and improve function and survival

Published in Law and Health Weekly, July 9th, 2005

Scientists have elucidated the effects of pre-, peri-, and postmyocardial infarction treatment with losartan in rats: effect of dose on survival, ventricular arrhythmias, function, and remodeling.

According to recent research from Canada, "Angiotensin receptor blockers (ARBs) reduce adverse left ventricular (LV) remodeling and improve LV function and survival when started postmyocardial infarction (MI). ARBs also reduce ventricular arrhythmias during ischemia-reperfusion injury when started pre-MI."

"No information exists regarding their efficacy and safety when started pre-MI and continued peri- and post-MI," said A. Pourdjabbar and colleagues,...

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