Istituto Nazionale Tumori Fond. G. Pascale
HIV-1 clade A virus-like particles elicit neutralizing antibodies
Published in Law and Health Weekly, July 30th, 2005
According to recent research published in the Journal of Virology, "We have recently developed a candidate human immunodeficiency virus type 1 (HIV-1) vaccine model, based on virus-like particles (VLPs) expressing gp120 from a Ugandan HIV-1 isolate of clade A (HIV-VLPA s), which shows the induction of neutralizing antibodies as well as cytotoxic T lymphocytes (CTL) in BALB/c mice by intraperitoneal (i.p.) administration.
"In the present study, immunization experiments based on a multiple-dose regimen...
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