Law and Health Weekly

NuVasive, Inc. - Study on XLIF minimally disruptive spine surgery procedure presented

NxStage Medical, Inc. - Medical device company files registration statement for IPO

OccuLogix, Inc. - Age-related macular degeneration trial data presented at conference

Oita University - K252a inhibited proliferation of ovarian cancer cells by upregulating p21(WAF1)

Okayama Prefectural University - Spinach glycolipids may abate cancer growth

Oncology Therapeutics Network - Oncology services company provides grant to oncology alliance

Oncolytics Biotech Inc. - Biotech company issued patent for method of producing infectious reovirus

Oregon Health & Science University - Challenges in systematic reviews that assess treatment harms outlined

Osaka City University - Chemically treated mice model natural killer T cell liver injury

Osaka City University - Rbx1 examined, multiple roles in ubiquitin ligase complex revealed

Osaka Medical Center - Preimplantation uterine MMP activity studied, role of neutrophils defined

Osaka University - E-cadherin endocytosis studied, nature of regulation defined

Osaka University - Elevation of aldosterone levels may be deleterious to ischemic heart disease

Osteologix Inc. - Phase I clinical trial for osteoporosis complete

Oxford Instruments - Medical device company and Cornell sign cooperative agreement

PAREXEL International Corporation - Pharma company acquires QdotPharma

PPD, Inc. - Discovery and development services company awarded NIH contract

Pacific Rheumatology Associates, Washington - Drug used to treat PD may be beneficial in treating fibromyalgia

PaperFree Medical - EMR company launches sales and marketing plan

Peking University, Beijing - Reduced folate carrier gene raises the risk for neural tube defects

Pennsylvania State University, Hershey - Carvedilol/digoxin combination therapy has synergistic effect on AF

Peptimmune, Inc. - Biotech company closes $20.4 million series C private financing

Personnel - Hartley named president of First Sun EA

PhRMA - DTC voluntary Guiding Principles receive association board preliminary approval

Phase 2 Consulting - Consulting company managing director named to board of Miracor Diagnostics

Philipps University Hospital, Marburg - Reports add new data to angioplasty research

Philipps-University of Marburg - Cationic microparticles developed as carriers systems for DNA vaccine

PhotoMedex, Inc. - Contract medical procedures names chief operating officer

Policlinico MultiMedic, Milan - Cryothermal catheter tip size affects cryoablation efficacy

Possis Medical, Inc. - Medical device company releases two new catheters

Power3 Medical Products - Proteomics company enters research agreement with research institute

Preferred Medical Marketing Corporation - Reimbursement monitoring system company announces four contracts

Princess Margaret Hospital, Hong Kong - Researchers' work adds to SARS body of knowledge

Procter & Gamble Co. - European Commission clears Gillette merger

Provectus Pharmaceuticals, Inc. - Final clearance for phase 1 clinical trial for PV-10 obtainted

Quality Care Solutions Inc. - Information technology company releases new version of application system

Queen Mary's School of Medicine and Dentistry - Insulin resistance modulates fibrosis and antiviral efficacy in hepatitis C

Queens University, Belfast - Brisk walking increases fitness and lowers cardiovascular risk

Quintiles Transnational Corp. - Kiyotaka Fujii named president, CEO by provider to healthcare, pharma industries

Ranbaxy Laboratories Limited - Pharma company receives U.S. FDA approval for Zidovudine Tablets

Reliv International, Inc. - Nutritional supplements provider opens network marketing in Germany

Rensselaer Polytechnic Institute, Troy - Laminin-5 induces osteogenic gene expression in MSCs through ERK-dependent path

Rhode Island Hospital - Two dosages of rotavirus vaccine found comparable in immunogenicity

Roche - Pharma company files for new indication of Tamiflu in Europe

Roche - sNDA filed for Biojector 200 in FUZEON administration

Rosetta Genomics - Dozens of novel human microRNAs identified

Roswell Park Cancer Institute, Buffalo - Neuropathy target esterase activity needed for optimal neurite initiation rate

Royal Free & University College, London - ADH1C genotype modifies relationship between alcohol consumption and CHD risk

Royal London Hospital - Utility of electrodiagnostic tests reviewed

Rush University, Chicago - Brain changes are more likely to present as dementia in women than in men

SARA Project, Washington, DC - Population-specific infant mortality rates guide HIV and infant feeding policy

SW Foundation for Biomedical Research, San Antonio - Recent findings in osteoporosis provide new insights

Saint Louis University Health Sciences Center - Research reveals why monkeypox outbreak in the U.S. was not deadly

Saint Louis University, Missouri - Study of Botox for severe underarm sweating yields positive results

Samaritan Pharmaceuticals, Inc. - Drug development company announces publication of Alzheimer preclinical studies

Samaritan Pharmaceuticals, Inc. - Phase 2b dosing begun in monotherapy trial for 'oral entry inhibitor' HIV drug

Sangamo BioSciences, Inc. - Developer of DNA-binding protein therapeutics reports Q2 2005 financial results

Sangart, Inc. - Phase 2 clinical trial for hemoglobin-based blood alternative Hemospan initiated

Savient Pharmaceuticals, Inc. - Pharmaceuticals company closes sale of global biologics manufacturing business

Schneider Children's Hospital, New Hyde Park - Prevalence of Gb virus C in perinatally HIV-infected children is small

Sekhsaria Institute of Public Health, Maharashtra - Alcohol and tobacco use among middle-aged and elderly in Mumbai characterized

Serbia Institute of Internal Medicine - BMI, body fat mass, and amenorrhea in ballet dancers examined

Sigma-Aldrich Corporation - Antibody array to identify protein kinase expression in cell, extracts launched

Sosei Co. Ltd - Japanese biopharmaceutical company to acquire Arakis for over $187 million

SourceOne Healthcare Technologies, Inc. - Companies renew agreement to make mammography CAD technology more available

Spectrum Pharmaceuticals, Inc. - Publication of key animal study results with chemotherapy adjuvant announced

Spectrum Pharmaceuticals, Inc. - U.S. Patent office sends allowance for attention deficit, hyperactivity drug

St. Bartholomew's & The London, U.K. - Single dose of chemotherapy is as effective as radiotherapy

St. Jude Children's Research Hospital - Solid-tumor biopsy may replace surgery to get diagnostic specimens

State University of New York-Downstate, Brooklyn - Carbapenem-resistant K. pneumoniae rapidly spreading in New York City

StemCyte, Inc. - Umbilical cord blood stem cell bank-focused company completes round of financing

Substance Abuse & Mental Health Services Admin. - Treatment admissions sharply up for methamphetamine, narcotic pain medications

Sungkyunkwan University - New findings in the area of uterine papillary serous carcinoma described

Sungkyunkwan University, Seoul - DNA MMR deficiency in H. pylori infection increase mutated risk in GI mucosa

SuperGen Inc. - Cancer-, blood-focused pharmaceutical company reports Q2 2005 financial results

SureScripts - Pharmacy franchisor to provide discounts on electronic prescribing transactions

Swiss Federal Inst. of Technology, Zurich - The proteinase ADAMTS1 alters fibroblast and endothelial cell migration

Symmetry Medical Inc. - Orthopedics device provider prices equity offering

TNO Nutrition & Food Research, AJ Zeist - Oral benzene exposure alters gene expression in rodent livers

TNO Prevention and Health, Leiden - Assay is new method for studying TAFI in cardiovascular disease

Tel Aviv University - Peptides derived from HIV-1 reverse transcriptase inhibit viral integrase

Teva Pharmaceutical Industries Ltd. - Generic drug company announces record Copaxone sales of $291 million in Q2

Teva Pharmaceutical Industries Ltd. - U.S. FDA grants tentative approval of generic antihistamine tablet

Tokyo Medical & Dental University - Researchers detail new studies and findings in the area of proteomics

Tokyo Medical and Dental University - Fermented P. tinctorium Aiton extract suppresses acute HIV-1 infection

Tokyo Metropolitan Institute of Gerontology - High arterial pulse wave velocity may be risk for poor cognitive function

Transcend Services, Inc. - Medical transcription company reports 74% revenue increase, $0.03 per share loss

Transgene SA - New data illuminates research in cancer vaccines

Trimeris, Inc. - Virus-focused biopharmaceutical company reports Q2 2005 financial results

Tufts University, Boston - For a healthier heart, don't go against the grain

Tufts University, Boston - Lupus patients have abnormally high frequencies of EBV-infected cells

U.K. Health Protection Agency, London - Sequence-based L. pneumophila typing epidemiologic concordant/discriminatory

U.S. Centers for Disease Control & Prevention - CDC releases extensive survey of Americans' exposure to environmental chemicals

U.S. Centers for Disease Control & Prevention - Methods for capture-recapture analysis without identifiers developed

U.S. Centers for Disease Control & Prevention - U.S. vaccination rates surpass Healthy People 2010 goal

U.S. Department of Agriculture - Mutant virus protects against virulent Marek's Disease strain

U.S. Food & Drug Administration - Influence of erythromycin A on aquaculture microbes examined

U.S. Food & Drug Administration - SEN virus infection not major cause of hepatocellular carcinoma

U.S. National Cancer Institute - Dietary cancer-chemopreventive compounds reviewed

U.S. National Institutes of Health - G protein beta studied, interaction with glucocorticoid receptor clarified

U.S. National Institutes of Health - Medroxyprogesterone empowers the Nm23-H1 metastasis suppressor gene

U.S. National Institutes of Health - New data illuminates research in malaria vaccines

U.S. National Institutes of Health - Recent findings illuminate research in malaria vaccines

U.S. National Institutes of Health - Research add new data to virology body of knowledge

U.S. Natl. Eye Institute - Trained nurses and laypersons perform well as preschool vision screeners

U.S. Natl. Institutes of Health - Multi-species genome comparison sheds new light on cancer mutations

U.S. Uniformed Services Univ of Hlth Sciences - CD107 cytotoxicity assay effective for monitoring cancer trials

U.S. VA Medical Center, New Orleans - Bombesin and somatostatin analogs repress glioma growth factors

UCLA Center for Health Policy Research - Study finds that HMOs should be part of California's solution to obesity crisis

Umea University - NK-1 receptor expression affects islet cells in diabetic mice

Umea University Hospital - The ST change vector magnitude can exceed ischemic thresholds during higher HRs

United Devices - Free online health assessment from the American Diabetes Association available

Univ. of California, Irvine - HIV-1B and C subtypes have different epidemic potentials

Univ. of California, Los Angeles - Research add new data to oncology body of knowledge

Univ. of Missouri, Columbia - Researcher promotes knowledge of asthma for teachers

Univ. of Texas, Houston - Circulating stem cells play small role in lung repair

Universidad Autonoma, Madrid - Key endoglin isoforms have contrasting effects on tumor development

University College London - New clues for the understanding of dementia

University College, London - Single-pill amlodipine/atorvastatin reduces both BP and cholesterol

University Hospital - Energy intake and expenditure in girls with type 1 diabetes examined

University Hospital Balgrist, Zurich - Botulinum toxin type A reduces neurogenic detrusor overactivity

University Hospital Schleswig Holstein, Kiel - Monocyte-derived Neohepatocytes developed for autologous cell therapy

University Hospital of Patras, Rion - Randomized, phase II study of optimal colorectal chemotherapy conducted

University Hospital of Valme, Seville - Combined models assess hepatitis C-related liver fibrosis

University Medical Center, Utrecht - Cardiac death is increased on Monday, more manifest in nonhospitalized patients

University of Adelaide, South Australia - Growth factor independent-1 repression of CYP27B1 promotes prostate cancer

University of Alabama - Condom slip-ups invite STD infection

University of Alberta - Cytotoxic T cell kinase activity examined, regulation clarified

University of Alberta - Study explores plant phenotypic plasticity belowground

University of Amsterdam - Safety of D-dimer test to diagnose suspected acute pulmonary embolism assessed

University of Athens - Abdominal lymphadenopathy has ties to post-transfusion chronic hepatitis C

University of Athens - Radiation doses during transcatheter closure determined in children

University of Barcelona - Three factors predicted lack of response to cardiac resynchronization therapy

University of Birmingham - Health, responsibility, and choice of the public examined

University of Bonn - HSJ1 analyzed, identity as neuronal shuttling factor revealed

University of California, Davis - HAART suppresses viral load in macaques infected with RT-SHIV

University of California, San Francisco - Telomerase depletion through RNA interference stunts cancer cell growth

University of California, San Francisco - Uniform controls back the integrity of gene silencing approaches

University of Cambridge - Lentiviral vectors containing hammerhead ribozymes end hepatitis B activity

University of Cambridge - Peptide from polyoma virus protein enhances gene delivery to epithelium

University of Catania - Modeling and simulation of cancer immunoprevention vaccine presented

University of Chicago - Dopamine transporter genotype affects methylphenidate efficacy

University of Cincinnati - "Stop and go" traffic increases infant wheezing

University of Erlangen-Nurnberg - Threshold tracking detects receptor potentials in rat skin nociceptors

University of Fed Santa Maria - Humoral response against LMW antigens important for detection of latent TB

University of Freiburg - Treatment of bladder cancer with mistletoe extract may decrease recurrence

University of Genoa - Utility of videocapillaroscopy in diagnosis reviewed

University of Georgia - Differentiation of Mycoplasma gallisepticum strains described

University of Gottingen - Extracardiac ICD successfully implanted in small infant

University of Groningen -  S. thermophilus lactose transporter studied, subunit interactions defined

University of Halle-Wittenberg - Tumor genes with aberrant promoter methylation identified

University of Heidelberg - Uremia examined, impaired norepinephrine release revealed

University of Heidelberg, Mannheim - Experimental therapy with cannabinoids may be justified in some MS cases

University of Helsinki - Potential treatment of paralysis and brain disease described

University of Hohenheim - Olfactory cilia studied, formation and maturation monitored

University of Hong Kong - Findings in oncology provide new insights

University of Hospital N Norway - Cost-effectiveness of monoclonal antibody evaluated for metastatic breast cancer

University of Illinois - Antipsychotics increase type 2 diabetes risk in schizophrenia patients

University of Kent, U.K. - Evidence points to role of arsenic in the madness of King George III

University of Kuopio - Genes are found to be upregulated in preeclampsia

University of Kuopio - HIV-1 TAT protein transduction domain constructs enhance ganciclovir toxicity

University of Laval, Quebec City - Insomnia Severity Index in cancer patients empirically validated

University of Laval, Quebec City - Phenobarbital response unit studied, binding sites elucidated

University of London Imperial Coll Sci Tech & Med - TGF-beta prevents eosinophilic lung disease but impairs pathogen clearance

University of Louisville - Bacteriemias induced by periodontal procedures are at lower level than reported

University of Louisville - Correctable sources of disparities in cancer among minority elders identified

University of Manchester - Exciplex-based probes detect DNA insertions and mismatches

University of Manchester, U.K. - Diabetic nerve therapy shows "striking" results

University of Marmara - Biochemical and behavioral indices related to BMI in children examined

University of Maryland - Apical bile acid transporter examined, role of cysteines clarified

University of Maryland - Gene therapy induces tolerance to factor VIII inhibitors

University of Medicine of Berlin - Findings describe new data in liver cancer research

University of Melbourne - Molecular shape-shifters linked to brain disease

University of Melbourne - Study compares mental health status of early adult & mid-life women

University of Miami - Intraocular lens type doesn't affect outcome in eyes with poor capsular support

University of Miami - Weight loss increases systolic and early diastolic velocities

University of Michigan - "Achilles' heel" of the herpes virus possibly found

University of Minnesota - Nicotine-specific antibodies reduce nicotine distribution to brain

University of Missouri - Pituitary melanotropes studied, GABA_B receptor subunit regulation defined

University of Munich - Researchers describe findings in diagnostics studies

University of Naples Federico II - PLGA microspheres with decoy oligonucleotide block nuclear factor-kappa B

University of Navarra, Pamplona - CT-1 protects cardiomyocytes via gp130/LIFR

University of Navarra, Pamplona - Marker may be useful in identifying asymptomatic subjects at risk for CV disease

University of Nebraska -  Pseudomonas syringae chaperones analyzed, role in secretion clarified

University of Nebraska, Omaha - Researchers' findings advance cardiology research

University of North Carolina - Combination scanner may increase accuracy in detecting spread, recurrence

University of North Carolina, Chapel Hill - Recent findings in cardiovascular disease provide new insights

University of Oklahoma - Peripherin/rds analyzed, consequence of Cys->Ser mutation revealed

University of Oslo - Alpha₁ -adrenoceptor block may contribute to effects of carvedilol

University of Oslo - Dynamic bladder wall properties elucidated

University of Oslo - Putative regulatory T cells impaired in CB from hereditary allergy risk neonates

University of Paris - Salivary lactoferrin recognized by human herpesvirus-8

University of Perugia - AF was present in more than 20% of patients with first-ever stroke

University of Pisa - Anterior neural plate specification studied, function of Six3 revealed

University of Pittsburgh - Reports advance knowledge in pneumococcal vaccines research

University of Regensburg - Renal dysfunction may be cause of elevated marker concentrations

University of Regensburg - Retinoids promote lipid efflux from stimulated macrophages

University of Rochester - Full-weight dose chemotherapy improves outcomes in obese women with cancer

University of Rochester - Scientists offer new understanding of how immune system targets disease

University of Roma Tor Vergata, Rome - Antigene PNA targeted to proviral HIV-1 DNA inhibits viral replication

University of Saarland, Homburg - Serine-threonine kinase 15 is overexpressed in MCF7 breast cancer cells

University of Sao Paulo - Effect of bosentan treatment on surrogate markers determined

University of Sao Paulo - Incidence in Brazil estimated from neonatal screening results

University of South Florida - Benzodiazepines and anxiety disorders reviewed

University of Southern Alabama, Mobile -  P. falciparum FK506 has drug-independent calcineurin-inhibitory activity

University of Southern California - Cancer listed as risk factor for long-term cognitive deficits and dementia

University of Sydney - Mitochondrial dysfunction studied, proteomic and functional analyses reported

University of Sydney, Westmead - Researchers' data advance SARS coronavirus research

University of Sydney, Westmead - Rolling circle amplification is rapid/sensitive for SARS coronavirus detection

University of Toronto - Electrically evoked middle latency response determined in pediatric users

University of Toronto - Phlebotomy contributes to anemia in hospitalized patients

University of Toronto - Review examines new modalities for assessment of vascular health in SLE patients

University of Toronto - Study established optimal timing of data acquisition for enhanced MR angiography

University of Toulon-Var, Nice - Analysis is useful to identify ventilatory thresholds in exercise tests

University of Trent - Strain replacement in epidemic model with perfect vaccination reported

University of Tsukuba - Transgenic mice overexpressing SREBP-1a exhibit insulin resistance

University of Ulm - Immortalized bovine cells model the mechanics of diabetic eye disease

University of Ulsan - Lamivudine-induced seroconversion after hepatitis B relapse is short-lived

University of Utrecht - Techniques to assess endothelial function can be applied in pediatric patients

University of Valladolid - Early clinical results of biliopancreatic diversion reviewed

University of Warwick, Coventry -  Mycobacterium bovis can persist in farm environment outside of its hosts

University of Washington - Why a vaccine for meningitis?

University of Washington, Seattle - B-spline model studies multiple longitudinal biomarkers/survival in HIV/AIDS

University of Washington, Seattle - Studies advance knowledge in virology research

University of Wisconsin - Levetiracetam doesn't affect pharmacokinetics of adjunctive drugs

University of Wisconsin - Surgical referrals increasingly common for elderly patients

Uppsala University - Angiotensin receptor inhibition improves insulin secretion in islets

Utah Medical Products, Inc. - Medical products company reports financial performance for second quarter 2005

Utrecht University - Researchers report details of new studies and findings in the area of angiology

Vanderbilt University - New method can grow bone for grafts within a patient's body

VantageMed Corporation - Healthcare software company expects second quarter revenue of $3.8-$4.0 million

Ventracor, Ltd. - Company announces first U.S. implant of VentrAssist

Vertex Pharmaceuticals, Inc. - FDA grants fast track status for investigational HIV protease inhibitor

Vibra Healthcare LLC - Pennsylvania healthcare provider acquires eighth specialty rehab hospital

Vical Incorporated - Canadian marketing approval received on DNA IHNV virus vaccine for salmon

VioQuest Pharmaceuticals, Inc. - Agreement reached for acquiring Greenwich Therapeutics, anti-cancer compounds

VistaGen Therapeutics, Inc. - U.S. NIH awards $197,000 grant to develop drug candidate for neuropathic pain

Visx, Incorporated - Supplemental information reported on acquisition

Vrije Universiteit Brussel - Genetic approaches to CD4+ T cell response in cancer therapy reviewed

Wallaceville Animal Research Center - Studies add new findings to tuberculosis vaccines body of knowledge

Walter Reed Army Medical Center - Oropharyngeal vaccinia virus absent after smallpox vaccination

Waltham Center for Pet Nutrition, U.K. - Defective sweet taste receptor gene shapes cat cuisine

Washington University, St. Louis - Type 1 interferons are important components of the cancer immunoediting process

Wayne State University, Detroit - 5-DFUR and tamoxifen affected cytotoxicity in human mammary carcinoma cells

WellCare Health Plans, Inc. - Georgia community health department awards Medicaid managed care contracts

WellCare Health Plans, Inc. - U.S. CMS approves benefits company's managed care coverage expansion

WellChoice, Inc. - Health benefits company launches secure personal health record feature online

Wellcome Research Laboratories, Herts - TMP/SQX against P. gallinaceum infection prevents clinical malaria

Wellcome Trust Center for Human Genetics, Oxford - Widespread use of provocation testing is not recommended

Wellcome Trust Research Laboratories - Pointers for malaria treatment from cancer chemotherapy detailed

Westlakes Research Institute, Cumbria - Chromosome analysis performed in childhood cancer survivors and their offspring

Wistar Institute, Philadelphia - Innate-immunity effector cells marker of CD4+ cell loss in pediatric HIV/AIDS

World Health Organization - Infant feeding patterns and risks of death investigated

Wyeth - Pharmaceutical company launches educational campaign about menopause for women

XOMA Ltd. - Biopharmaceutical company retakes control of BPI product from Zephyr Sciences

XactiMed - Maryland hospital picks claims, remittance, denial management electronic system

Xechem International, Inc. - Biopharmaceutical company establishes sickle cell advisory board

Xenomics, Inc. - Infectious disease institute, DNA technologies developer sign research agreement

Xillix Technologies Corp. - Cancer diagnostic devices company names Rob Ngungu VP, quality, clinical affairs

Xsira Pharmaceuticals, Inc. - Postoperative analgesia for infusion found to be effective, company announces

Yale University - Drinking alcohol may lower risk of lymphoma

Yale University - Labeled peptides targeting a major integrin capture angiogenesis images

Yale University - Researchers detail new studies and findings in the area of breast cancer

Yamaguchi University, Ube - Human maid homologue useful marker protein in hepatocarcinogenesis

Yokohama City University - Biatrial pacing improves cardiac hemodynamics

aaiPharma Inc. - Xanodyne Pharmaceuticals makes winning bid to sell pharmaceuticals division

deCODE biostructures - Accelerated Technologies Center for Gene to 3D Structure established