Chiron Corporation
Research add new data to HIV/AIDS vaccines body of knowledge
Published in Law and Health Weekly, September 24th, 2005
Study 1: A priming-boosting regimen with recombinant proteins enhanced the potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques.
"DNA vaccines have been used widely in experimental primate models of human immunodeficiency virus (HIV), but their effectiveness has been limited. In this study, we evaluated three technologies for increasing the potency of DNA vaccines in rhesus macaques. These included DNA encoding Sindbis virus RNA replicons (pSINCP), cationic poly(lactide-co-glycolide) (PLG) microparticles for DNA delivery,...
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