St. George Hospital, London
Portal vein myocyte Ca2+ channels studied, facilitatory effect defined
Published in Law and Health Weekly, October 1st, 2005
"In rabbit portal vein smooth muscle cells, store-operated SOCs display multi-modal gating mechanisms. SOCs are activated by depletion of intracellular Ca2+ stores but also may be stimulated in a store-independent manner by noradrenaline acting on alpha-adrenoceptors and by diacylglycerol (DAG) via protein kinase C (PKC).
"In the present study we have investigated whether (Ins(1,4,5)P-3) modulates SOC activity in...
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