Law and Health Weekly

Nabi Biopharmaceuticals - Data shows Altastaph results in shorter duration of bacteremia and fever

Nagoya University, Aichi - Rho mediates endocytosis of epidermal growth factor receptor through endophilin phosphorylation

Nanjing Medical University - NORPEG expressed in human fetal testes, adult testes and spermatozoa

National Center of Neurology & Psychiatry, Tokyo - Ndrg2 promotes neurite outgrowth of differentiated PC12 cells

National Center of Neurology & Psychiatry, Tokyo - Upregulation of matrix protein transcripts related to atrophic myofibers found in XLMTM

National Chiao Tung University, Hsinchu - Fe₃ O₄ /TiO₂ core/shell nanoparticles detect phosphopeptides levels of 500pM

National Institute of Standards and Technology - U.S. NIST develops a healthcare IT standards repository

National Sun Yat-Sen University, Kaohsiung - Statins can improve lipid profiles in patients with hyperlipidemia

National University of Ireland, University College Cork - Radial cells in the spinal cord are precursors to radial glia

National University of Singapore - Mitochondrial permeability transition main effect of mitochondrial uncoupling, ROS is secondary

National University of Singapore - Simulation study developed to predict herb-drug metabolic interactions

NeoPharm, Inc. - Study results support feasibility of multimodality therapy for malignant glioma

Neose Technologies, Inc. - Biopharma company names George J. Vergis president and chief operating officer

New York State Department of Health - Cytochrome P450 and other biotransformation enzymes expressed in adult human nasal mucosa

New York University Hospital for Joint Diseases - Serum IL-6 is an accurate diagnostic marker of periprosthetic infection

Niigata University - Risk of neck cellulitis should be monitored for 1 year after neck dissection

North Hampshire Hospital, Basingstoke - Biopsy of resectable colorectal liver metastases causes tumor dissemination

Northwick Park Hospital & Clinic Research Center, Harrow - Contrast echo can be used to detect coronary artery disease in patients presenting with heart failure

Nova Southeastern University, Ft. Lauderdale - Reproductive hormones and menstrually related distress predict migraine activity

Nymox Pharmaceutical Corporation - Second safety analysis of prostate drug reveals no serious side effects

OCG Technology, Inc. - PrimeCare Systems awards license to Argentina-based Telemedica

OSI Systems, Inc. - U.S. FDA grants 510(k) approval for sale, distribution of anesthesia systems in U.S. market

Odense University Hospital - No survival benefit due to early initiation of adjuvant chemotherapy detected

Ohio State University - Intraepidermal epithelioid melanocytic dysplasia marked atypical mole phenotype

Ohio University - Chagasic serum inhibits Trypanosoma cruzi egress from tissue culture cells

OncoGenex Technologies Inc. - Phase II clinical trial of hormone refractory prostate cancer drug underway

Ophthalmic Imaging Systems - Ophthalmic digital imaging company launches four new products

Ophthonix - Vision technology company secures $17 million

Organon Pharmaceuticals USA Inc. - Pharma company appoints Terrence Moore as vice president

Osaka University - Association of beta₂ -microglobulin amyloid fibrils is thermally controlled

Osaka University - Donor leukocyte infusion may be a potential treatment for cytomegalovirus retinitis

Osaka University - Novel technique simplifies laparoscopic purse-string suturing during circular stapling anastomosis

Ospedale Riuniti Bergamo - Surgical palliation advised first for intestinal obstruction in ovarian cancer

Oxford BioMedica - Preliminary data shows renal cancer drug is safe and well tolerated

Oxford Ventures, Inc. - Holding company signs merger agreement to acquire Uluru

Oxigene, Inc. - Clinical trial affirms safety of vascular drugs in combination with radiotherapy

Pamela Youde Nethersole Eastern Hospital - Non-invasive ventilation for respiratory failure lowers intubation and death rates

Papworth Hospital, Cambridge - Heart transplants provide survival benefit with rigorous donor and recipient selection

Peking University, Beijing - Expansion capacity of mesenchymal stem cells after sex-mismatched SCT is damaged

Personnel - Axia Health Management appoints new chief medical officer, general counsel and VP of sales

Personnel - Charles E. Sessa, Jr., chairman of the board of trustees, to step down

Personnel - Daniel Dwyer joins Innovative Health Solutions as chief sales officer

Peter MacCallum Cancer Center, Melbourne - Progression-free survival increased after application of high-dose imatinib

Pfizer Global Research & Development - High-throughput HIV-1 full replication assay includes Vif as an antiviral target

Pharsight Corporation - Drug development software services company releases WinNonlin Validation Suite

Philanthropy - Carl's Jr. franchise restaurants raise $175,000 for breast cancer

Princess Margaret Hospital, Toronto - Clinical trial recommended to further test combination of carboplatin and PLD

Proteus - Patent granted for gene shuffling technology

Provincial Laboratory for Public Health, Calgary - Focus and Panbio flavivirus enzyme immunoassays useful for diagnosis

Purdue University, West Lafayette - Early awareness might prevent avian flu pandemic

Pusan National University - Costunolide inhibited telomerase activity in human breast carcinoma cells

QMed, Inc. - Health e Monitoring acquires assets of Disease Management Technologies

Quality Assurance - Thirty-one hospitals receive Texas Health Care Quality Improvement Award

Quarry Health Centre, Northbridge - Speculum self-insertion offers potential to reduce anxiety of sexual health screening

RAND Corporation - Many HIV-infected adults perceive discrimination by health care providers

Radboud University, Nijmegen - Adrenergic receptor stimulation attenuates glucose uptake in adipocytes

Ranbaxy Laboratories Limited - U.S. Food and Drug Administration grants final approval of Gabapentin

Raven Biotechnologies, Inc. - Biotech company raises $48.3 million for cancer research

Recom Managed Systems - Life sciences company appoints Keitt and Sosebee to cardiac services division

Regina Elena Institute for Cancer Research, Rome - Epirubicin, cisplatin and docetaxel were combined to treat metastatic gastric cancer

Roswell Park Cancer Institute, Buffalo - Genetic aberrations may be possible molecular fingerprint of radiation-associated breast cancer

Royal Children's Hospital, Brisbane - Researchers question persistent cough treatments for children

Royal Free & University College Medical School, London - Inflammation and hemostasis may increase cardiovascular risk from smoking

Royal Marsden Hospital National Health Services Trust, Sutton - Psychological response influenced breast cancer survival

Ruhr-University Bochum - Radiographic progression in infliximab patients show inhibition of structural damage

Ruhr-University Bochum - Standardization of nonhuman primate models needed to assess AIDS vaccines

Salzburg University - Novel protocol improves consistency and reduces morbidity

Schering AG - European Commission approves magnetic resonance angiography contrast agent

Scott's Food & Pharmacy - Keltsch Pharmacy changes name to align identity with branding

Seoul National University - Anti-obestic ligand GW501516 for PPAR-delta synthesized

Serono - Canvaxin phase III clinical trial for patients with stage III melanoma discontinued

Shanghai Jiao Tong University - Myelin-associated glycoprotein genotype linked to schizophrenia in Chinese Han

Shanghai Medical University - GABA and opioid peptide receptors are involved in sevoflurane-induced spinal cord antinociception

Shiraz University of Medical Sciences - Stromal cell-derived factor-1 gene variants heighten lung cancer susceptibility

Shire Pharmaceuticals Group plc - Petition submitted to U.S. FDA for more rigorous bioequivalence testing for generic Adderall XR

Showa General Hospital, Tokyo - Technique reliably measures blood flow volume and artery diameter

Sinclair Pharma plc - Pharma company signs copromotion agreement for Atopiclair

Skinvisible Pharmaceuticals, Inc. - EMD Chemicals enters partnership for worldwide distribution of Invisicare

Sontra Medical Corporation - Results from transdermal vaccination safety and feasibility studies reported

SourceOne Healthcare Technologies, Inc. - Medical imaging systems distributor signs agreement with GPO HealthTrust

Southwest Foundation for Biomedical Research - Researchers discover gene on chromosome 15 that regulates inflammation

Specialty Laboratories, Inc. - Reference lab, Roche Diagnostics signs agreement to offer assay for genetic testing

Spectranetics Corporation - Colorado laser technology company named top performer in Technology Fast 50 program

St. Helier Hospital, Surrey - Acceptable level of maternal and neonate side effects found with patient-controlled analgesia

St. Jude Children's Research Hospital, Memphis - Ependymomas in other CNS locations appear to arise from radial glia cells

St. Jude Children's Research Hospital, Memphis - Retinoblastoma researchers demonstrate a new treatment with drug combination

St. Michael's Hospital, Toronto - Improving the health of the homeless requires coordinated care

St. Vincent's Hospital, Dublin - Study declares new markers of ovarian cancer be judged against CA125

Statens Serum Institute, Copenhagen - Cancer susceptibility in nasopharyngeal carcinoma families described

Stiefel Laboratories - Pharma company names Nancy Oaks as vice president of sales for U.S. Rx division

Sungkyunkwan University, Seoul - AFB smear-positive sputum may indicate nontuberculous mycobacteria versus pulmonary TB

Sungkyunkwan University, Suwon - Limulus amoebocyte lysate assay detects endotoxin in hepatitis B virus vaccine

Surface Logix - Biological microsystems developer appoints John Wm. Ferkany as vice president

Surface Logix Inc. - Phase 1 trial of inhibitor to treat endothelial dysfunction achieves target profile

Taipei Medical University - Econazole induces G₀ /G₁ cell cycle arrest and caspase 8-independent apoptotic signaling

Taipei Medical University - Small-volume ultrasonic nebulizer shows promise for ophthalmic drug delivery

Taiwan National University - Multiple myeloma cytogenetic abnormalities in Asia compared with those documented in the West

Tarbiat Modarres University, Tehran - Low 5-year survival rate from gastric cancer attributed to delayed diagnosis

Technion Israel Institute of Technology, Haifa - Pomegranate juice inhibits oxidized LDL uptake and cholesterol biosynthesis in macrophages

Tel Aviv Sourasky Medical Center - Treadmill walking acts as external pacemaker to improve gait stability

Thomas Jefferson University, Philadelphia - Mitochondria and endoplasmic reticulum work together to control apoptotic proteins

Threshold Pharmaceuticals - Pharmaceutical company announces follow-on offering of 6,250,000 common stock shares

Tokyo Medical University - Optical coherence tomography can detect early bronchial tumors

Toronto General Hospital - High C2 levels associated with fewer episodes of cellular rejection after heart transplantation

TorreyPines Therapeutics, Inc. - New alliance signed regarding genetic research program for Alzheimer disease

Tulane National Primate Research Center, Covington - Simian immunodeficiency virus disrupts extended lengths of the blood-brain barrier

Tulane University, New Orleans - Superoxide anion and nitric oxide have interactive effects on blood pressure and renal hemodynamics

Turku University Hospital - Investigators explored association of sex hormones with risk of ovarian cancer

U.S. Centers for Disease Control & Prevention - Efforts needed to assure performance of health workers in low-resource settings

U.S. Centers for Disease Control & Prevention - Influenza vaccination coverage falling short in United States

U.S. Centers for Disease Control & Prevention - Method is developed to determine avidity for H. influenzae antibodies

U.S. Centers for Disease Control & Prevention - Total and percent free PSA levels among U.S. men reported

U.S. Food & Drug Administration - IL-4 receptor is promising target for advanced ovarian cancer therapy

U.S. National Cancer Institute - Development of histone deacetylase inhibitors as anticancer agents reviewed

U.S. National Institute of Child Health & Human Development - Planned caesarian section is safe and effective for preventing transmission of HIV

U.S. National Institutes of Health - Genetically engineered live bacteria block HIV fusion and entry

U.S. National Institutes of Health - Human parainfluenza virus type 1 vaccine candidate is attenuated and effective

Umea University Hospital - Beta blockers should not remain first treatment for high blood pressure

Uniformed Service University of Health Science, Bethesda - Endogenous neuregulin restores radial glia in a model of cortical dysplasia

United Network for Organ Sharing - Nonprofit organ donation organization receives transplant network contract

Universidad Autonoma de Madrid - Obesity and weight loss linked to high health service use among elderly

Universita Politecnica delle Marche, Ancona - Anemia used as prognostic factor in patients undergoing resection for lung cancers

Universitatsklinikum Schleswig-Holstein, Lubeck - Doctors are advised to carefully assess causes of traumatic brain injury in children

University Clinic, Basel - Signs and symptoms are only moderately helpful in diagnosing CHF

University Clinic, Dusseldorf - Glucose deprivation preconditions isolated rat hearts

University College London - Differential restriction of HIV-2 and SIVmac by TRIM5 alleles studied

University College London - Molecular changes in prostatic cancer discussed

University Hospital Frankfurt - Circulating CD34+ cells increase 10 hours after G-CSF administration

University Hospital Gasthuisberg, Louvain - QRS shortening in tetralogy of Fallot is related with better exercise performance

University Hospital of Jena - Coping strategies for families of elderly cancer patients described

University Hospital, Angers - Less invasive surgery effective in treatment of GERD

University Hospital, Hamburg - Pulse contour-derived cardiac index accurate during changes of preload and aortic impedance

University Hospital, Maastricht - Adenosine induces vasodilatation in the human hypertensive kidney

University Hospital, Modeno - Hydroperoxides are accurate markers of acute oxidative injury, unlike malondialdehyde

University of Amsterdam - Biliary drainage procedure proposed for palliative management of hilar cholangiocarcinoma

University of Amsterdam - Endocrine late effects occurred from multi-modality treatment of neuroblastoma

University of Arizona - Neutrophil generated HOCl causes oxidative stress during reperfusion injury phase

University of Athens - Vitamin C may have beneficial effects on NO bioavailability induced by L-arginine

University of Bern - Endothelial nitric oxide synthase is non-essential in fibrosis and portal hypertension

University of Birmingham - Report describes variations in goal achievement between starting doses of statins

University of Bologna - Poly(vinyl alcohol)-co-oleylvinyl ether derivative elicits cytotoxic response in tumor

University of Bonn - Ti₆ Al₄ V and Ti₆ Al₇ Nb reduce microvasuclar complications compared to CoCrMo

University of Calabria, Rende -  Achillea ligustica extracts possess antidiabetic activities

University of Calgary - Quorum-sensing mutations affect B. cenocepacia biofilm attachment and stability

University of California, Davis - Ophthalmologist to examine ancient Chilean mummy eyes

University of California, Los Angeles - Implant-based facial prosthesis has higher user ratings than adhesive-based prosthesis

University of California, San Diego - Hyperthyroidism resulted in greater K⁺ current increases in right vs. left atrium

University of California, San Francisco - Insurance company rewards to doctors and hospitals may not improve care

University of California, San Francisco - Non-RD1 gene cluster required for Mycobacterium tuberculosis Snm secretion

University of Chicago Hospitals - TEE examinations are associated with low risk of esophagogastric trauma

University of Cologne - Rituximab appears to be an effective treatment for refractory pemphigus

University of Colorado - Shank2E binds NaPi cotransporter at the apical membrane of proximal tubule cells

University of Connecticut - Article summarizes effects of fatty acids on plasma lipid concentrations

University of Dusseldorf - Hepatitis B vaccine programs in Germany should be extended to include susceptible populations

University of Edinburgh - Bovine tuberculosis detected in wildlife of northern Tanzania

University of Frankfurt Klinikum - Valproic acid stimulates CMV replication in retinal pigment epithelial cells

University of Geneva - Transcription factor selectively increases ion permeability and modulates tight junction proteins

University of Gottingen - NT-proBNP or troponin testing: good first step to identify risk with pulmonary embolisms patients

University of Guelph - Integrin trafficking is required for spreading in CHO cells

University of Helsinki - Matrix metalloproteinase-3 and interleukin-1 beta are important in rheumatoid arthritis

University of Houston - Targeted education affects women's knowledge and attitudes about breast cancer

University of Illinois - Emotional impairment linked to cognitive deficits in bipolar children

University of Kentucky - Nutrition expert evaluates new weight-loss medication

University of Kentucky - Recommendations for cancer caregiving outlined

University of Lausanne Hospital - Tissue engineered fetal skin constructs improve healing of pediatric burns

University of Leipzig - Outcome of EERPE deemed on par with laparoscopic transperitoneal radical prostatectomy

University of Ljubljana - Nerve growth factor-induced histamine release from mast cells involves a signaling pathway

University of London - Bacterial substrate coating improves colonic targeting of single-unit tablets

University of London - Isopimaric acid shows activity against multidrug- and methicillin-resistant S. aureus

University of London Kings College - Cytotoxic plants from Malaysia and Thailand used traditionally to treat cancer

University of Louisiana School of Pharmacy - Calcitonin boosts prostate cancer growth by stimulating intratumoral vascularization

University of Manitoba, Winnipeg - Treatment response in head and neck cancer predicted by MR spectroscopy

University of Maryland School of Medicine - Drug combination against AIDS-related infections also effective against malaria

University of Melbourne - Mammographic density and bone mineral density unrelated to genetic determinants

University of Melbourne - Use of FDG-PET offers cost and clinical outcome benefits for lung cancer staging

University of Milan - Fibromyalgia patients have enhanced CV sympathetic activity while recumbent

University of Milan - U-benzene good biomarker for low-level occupational and environmental benzene exposure

University of Missouri - H₂ O₂ activation of p38 MAPK pathway shown to properties in astrocytes

University of Nebraska - GSL extract reduces cholesterol absorption and plasma non-HDL levels in hamsters

University of North Carolina - HIV-1 RNA and CD4 count moderately but inconsistently associated with malaria parasitemia

University of Oslo - Higher enterolactone levels may reduce breast cancer risk

University of Pavia - Increased aldosterone may link depression to unfavorable vascular events

University of Pennsylvania - Interleukin-12 enhances CD8 SIV vaccine immune response

University of Pennsylvania School of Medicine - Notch signaling may have role in autoimmune disorders

University of Pisa - Nasal torquetenovirus load associated with spirometric indices

University of Queensland - Climate dependent variations in fly abundance may contribute to transmission of RHDV

University of Regensburg - Temporary cements do not affect bond strength of ceramic luted to dentin

University of Rhode Island - Lab-on-a-chip research leads to international engineering PhD program

University of Rochester - ImmunoCyt endorsed as sensitive test for detecting bladder cancer

University of Rome La Sapienza - Protein is undetectable in patients with no response to hepatitis C therapy

University of Saskatchewan - Myristoyltransferase expression elevated in epilepsy

University of Saskatchewan - Researchers able to predict a child's final adult height

University of Sheffield - Zoledronic acid and doxorubicin induced synergistic levels of apoptosis

University of Shizuoka - Continuous paroxetine treatment reduces SERT ligand binding sites and protein expression

University of Southern California - Atypical antipsychotics for dementia may result in increased risk of death

University of Stellenbosch, Tygerberg - Reinfection and mixed infection cause changing MTB drug-resistance patterns

University of Stockholm - Creatinine clearance superior to serum creatinine for predicting early mortality

University of Tennessee - Decreased H19 expression associated with anticancer activity in dedifferentiated cell clones

University of Texas SW Medical Center, Dallas - UVB-induced immunosuppression due to augmented dectin-2 expression in Langerhans cells

University of Texas, Austin - Duloxetine is new medication for treatment of major depressive disorder

University of Thessaly, Larisa - HCV-RNA transcription-mediated amplification detects infection in hemodialysis patients

University of Tokyo - Loss of TSLC1 expression in lung adenocarcinoma associated with poor prognosis

University of Toronto - Maintenance infliximab treatment linked to improved bone mineral density in Crohn disease

University of Toronto - Neural stem cells partition DNA asymmetrically

University of Toronto - Pain scores look similar in patients given different liver biopsy procedures

University of Toronto - Therapeutic use for umbilical cord blood may broaden

University of Turin - New cut-off limits of GH response determined for use in obese patients

University of Udine - Review examines role of prothrombotic state and lipoprotein(a) as atherosclerotic risk factors

University of Ulsan College of Medicine, Seoul - Laparoscopic surgery declared effective alternative to laparotomy for cancer treatment

University of Ulsan, Seoul - Immobilization stress alters and causes oxidative damage in the nigrostriatal system

University of Ulsan, Seoul - Novel balloon sheath performs well in gastrointestinal phantom study

University of Utah - Scientists find molecular structure relevant to cell growth and cancer

University of Utrecht - HemoCue glucose analyzer results are comparable with YSI glucose oxidase analyzer

University of Valladolid - Imaging of calcium oscillations in intact pancreatic islets reported

University of Vermont - Antibodies in lymphocyte supernatant assay less sensitive than antibody-secreting cell assay

University of Virginia - Virginia health system wins renewal of $6.2 million grant for Crohn disease research

University of Washington - Interferons act to allow clonal expansion in response to viral infection

University of Washington - Low salivary levels of antimicrobial peptides may contribute to dental caries susceptibility

University of Western Australia - Management of menopausal symptoms in cancer patients requires multidisciplinary approach

University of Wisconsin - Anterior iliac crest reconstruction reduces pain after bone graft harvest

University of Wisconsin - Protein-acrylamide copolymer hydrogels quantitatively determine tyrosine kinase activity

University of Zurich Hospital - Flow cytometry method quantifies isotype-specific ABO blood group antibodies

VA Palo Alto Health Care System - Latin Americans with chronic hepatitis C are less likely to initiate or continue therapy

Vaccine Safety - Newest study finds no link between MMR vaccine and autism

Varian Medical Systems - Radiotherapy equipment contract extended for 7 years at U.K. oncology center

Ventaira Pharmaceuticals - John Denny named VP, product development, by drug delivery devices developer

Vita Salute University, Milan - Amprenavir significantly lowers plasma atazanavir levels when given in combination

Vrije Universiteit Brussel - Study proposes VHH framework of cAbBCII10 candidate for human therapies

Wake Forest University, Winston-Salem - Gamma knife is effective in treating trigeminal neuralgia

Wake Forest University, Winston-Salem - Parathyroidectomy was associated with decreased calcification in dialysis patients

Wake Forest University, Winston-Salem - Steroids treatment may result in more severe chickenpox

Washington Hospital Center - Cryoplasty effectively treats challenging peripheral artery blockages

Wayne State University, Detroit - Prenatal exposure to alcohol may cause visual problems in infants

Wellcome Trust Sanger Institute - Glycol methacrylate resin provides universal tissue microarray format

West Pharmaceutical Services Inc. - Don McMillan named division president by medical devices manufacturing company

Wilmer Eye Institute - Wavefront-guided LASIK effective for correction of low-to-moderate myopia with astigmatism

Wolfson Wellcome Biomedical Laboratories -  Schistosoma haematobium interacts with S. guineensis in Cameroon

World Health Organization - Clinical malaria increase attributable to HIV-1 epidemic in sub-Saharan Africa

Wuhan University -  Helicobacter pylori eradication recommended in patients with duodenal ulcer

Wyeth - Drug company comments on Q3 2005, puts full-year earnings growth in high single digits

XactiMed - McLeod Health selects claims management solution

Xeral-Calde Hospital, Lugo - Vascular endothelial growth factor variant may increase giant cell arteritis complications

Yonsei University, Seoul - Soft-tissue axillary masses profiled by sonographic appearances

Zhongshan Hospital - Bone marrow stem cell transplants improve heart function

Zonare Medical Systems, Inc. - Sacred Heart Medical Center acquires Zone Sonography technology

eResearchTechnology, Inc. - ECG services provider reports record-breaking $32 million in Q3 contracts

eyeonics, inc. - Maker of accommodating interocular lens reports Q3 2005 sales revenue growth of 51%