Medical University of Silesia, Katowice
Platelet glycoprotein IIIa genotype determines effect of aspirin on postoperative bleeding
Published in Law and Health Weekly, November 26th, 2005
"The presence of the glycoprotein IIIa allele PlA2 is associated with enhanced thrombin formation and an impaired antithrombotic action of aspirin, which could favor coronary thrombosis," according to surgeons in Poland, who "wondered whether PlA1/A2 genetic polymorphism could affect the postoperative bleeding in patients undergoing coronary artery bypass grafting."
To answer this question, W. Morawski and colleagues at the Medical University of Silesia conducted a "randomized, double-blind study," which...
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