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Dalhousie University

Group A Streptococcus vaccine efficacious in healthy adults

Published in Law and Health Weekly, December 3rd, 2005

A 26-valent group A Streptococcus vaccine was safe and efficacious in healthy adult volunteers.

According to recent research from Canada and the United States, "Group A streptococcus (GAS) causes illness ranging from uncomplicated pharyngitis to life-threatening necrotizing fasciitis, toxic shock, and rheumatic fever. Attempts to develop an M protein-based vaccine have been hindered by the fact that some M proteins elicit both protective antibodies and antibodies that cross-react with human tissues."

"New molecular techniques have allowed the previous obstacles to be largely overcome. The vaccine is comprised of four recombinant proteins...

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