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Kumamoto University

Recent studies add new data to HIV/AIDS vaccines research

Published in Law and Health Weekly, December 17th, 2005

Investigators in Japan and France have published new HIV/AIDS vaccines data.

Study 1: Scientists have identified an HLA-A*3101-restricted cytotoxic T-lymphocyte (CTL) response to human immunodeficiency virus type 1 (HIV-1) in patients with chronic HIV-1 infection.

"Virus-specific cytotoxic T-lymphocyte (CTL) responses are critical in the control of human immunodeficiency virus type 1 (HIV-1) infections. As several HIV-1 CTL epitopes restricted to many HLA types are already known, we aimed at identifying the CTL epitopes restricted by HLA-A*3101 in an effort to expand the epitope repertoire available for the development of potential T cell-mediated...

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