Osaka City University
Hormesis and dose-response-mediated mechanisms in carcinogenesis discussed
Published in Law and Health Weekly, December 24th, 2005
According to a study from Japan, "Recently the idea of hormesis, a biphasic dose-response relationship in which a chemical exerts opposite effects dependent on the dose, has attracted interest in the field of carcinogenesis. With non-genotoxic agents there is considerable experimental evidence in support of hormesis and the present review highlights current knowledge of dose-response effects."
"In particular, several in vivo studies have provided support for the idea that non-genotoxic carcinogens may inhibit hepatocarcinogenesis at low doses. Here, we survey the...
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