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Cornell University, Weill Medical College, Ithaca

Vaginally delivered SIV-cell fusion inhibitors protect macaques from SHIV infection

Published in Law and Health Weekly, December 31st, 2005

Vaginally delivered SIV-cell fusion inhibitors protect macaques from vaginal SHIV infection.

According to a study from the United States, "Human immunodeficiency virus type 1 (HIV-1) continues to spread, principally by heterosexual sex, but no vaccine is available. Hence, alternative prevention methods are needed to supplement educational and behavioral-modification programs. One such approach is a vaginal microbicide: the application of inhibitory compounds before intercourse."

"We have evaluated the microbicide concept using the rhesus macaque 'high dose' vaginal transmission model with a CCR5-receptor-using simian-human immunodeficiency virus...

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