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Hanusch Hospital, Vienna

Study of triglycerides and mitochondrial function offers mechanism of diabetes development

Published in Law and Health Weekly, January 14th, 2006

Study of muscle triglycerides and mitochondrial function offers possible mechanisms for the development of type 2 diabetes.

"Obese and type 2 diabetic (T2DM) adolescents present with reduced insulin-stimulated glucose disposal and elevated intramyocellular lipids (IMCL) indicating comparable muscular insulin resistance and increased flux of free fatty acids (FFA) as in adult patients. In humans, the causal relationships between obesity and insulin resistance were examined in detail over the last years," scientists in Austria report.

M. Roden and colleagues at Hanusch Hospital in Vienna explained, "The impact of genetic factors was analyzed in young...

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