Klinikum Philipps University, Marburg

H. pylori eradication results in complete histological remission of MALT lymphoma

Published in Law and Health Weekly, January 14th, 2006

Helicobacter pylori eradication results in continuous complete histological remission of MALT lymphoma.

"Cure of infection induces remissions in most patients with early stage Helicobacter pylori(Hp) positive gastric MALT (mucosa-associated lymphoid tissue) lymphoma (GML). We tracked the long-term stability of remissions in this prospective, multicenter trial."

"In 120 patients with stage 1 disease, we performed sequential endoscopic-bioptic follow-up after Hp eradication and polymerase chain reaction of the rearranged immunoglobulin heavy chain gene. The status of t(11;18) was assessed in 65 patients. Median follow-up was 75 months...

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Source: Law and Health Weekly (2006-01-14)

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