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University of Minnesota

Type 1 diabetes cure may be found in islet transplants

Published in Law and Health Weekly, March 18th, 2006

Researchers at the University of Minnesota's Diabetes Institute for Immunology and Transplantation have successfully reversed diabetes in monkeys using transplanted islet cells from pigs.

Survival of pig islet transplants was made possible with a novel immunosuppressive protocol. Graft survival did not require genetic modification of donor pigs or coating or encapsulation of donor islets.

Researchers have already had success reversing type 1 diabetes in humans through islet transplantation; however, the demand for islet cells grossly outweighs the supply. To make islet transplantation a viable solution for the tens of thousands of people with...

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