Nagasaki University
Bladder cancers produce strong lymphangiogenesis and angiogenesis signals
Published in Law and Health Weekly, April 8th, 2006
"Lymph vessel density (LVD) and microvessel density (MVD) correlate with the malignant potential of tumors and patient survival. Vascular endothelial growth factors (VEGF)-A, VEGF-C, and VEGF-D could modulate LVD and MVD," scientists in Japan report.
"We investigated the clinical and prognostic significance of LVD and MVD on lymphangiogenic and angiogenic function of VEGF-A, VEGF-C, and VEGF-D in human bladder cancer. We reviewed tissue samples from patients with nonmetastatic bladder cancer who had undergone transurethral resections (n=126). The densities of D2-40-positive...
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