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Eli Lilly & Company

Exenatide dose reduced postprandial plasma glucose excursions in type 2 diabetes

Published in Law and Health Weekly, April 15th, 2006

Exenatide treatments demonstrated reductions in postprandial plasma glucose excursions in type 2 diabetes.

"Exenatide is an incretin mimetic whose effect on glycemic control in patients with type 2 diabetes is currently under investigation. This study assessed the effect of injection time relative to a standardized meal on postprandial pharmacodynamics of exenatide in patients with type 2 diabetes," researchers in England report.

H. Linnebjerg and colleagues at Eli Lilly explained, "Eighteen patients participated in this single-center, open-label, placebo-controlled, randomized, six-way crossover study. Patients received subcutaneous injections of...

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