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University of Oxford

Researchers' findings from the United Kingdom, India and United States advance malaria research

Published in Law and Health Weekly, August 12th, 2006

Investigators in the United Kingdom, India and United States have published new malaria data.

Study 1: Recombinant fowlpox strain FP9 and modified vaccinia virus Ankara vaccines are safe and effective against liver-stage P. falciparum malaria in non-immune volunteers.

"The ability to generate potent antigen-specific T cell responses by vaccination has been a major hurdle in vaccinology. Vaccinia virus and avipox viruses have been shown to be capable of expressing antigens in mammalian cells and can induce a protective immune response against several mammalian pathogens. We report on two such vaccine constructs, modified vaccinia virus Ankara...

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