Medical College of Georgia, U.S.
Endotoxin-induced cardiac dysfunction is prevented by polyethylene glycol-superoxide dismutase
Published in Law and Health Weekly, August 12th, 2006
According to recent research from the United States, "Sepsis produces significant mitochondrial and contractile dysfunction in the heart, but the role of superoxide-derived free radicals in the genesis of these abnormalities is not completely understood. The study was designed to test the hypothesis that superoxide scavenger administration prevents endotoxin-induced cardiac mitochondrial and contractile dysfunction."
"Four groups of rats were studied, and animals were injected with either saline, endotoxin, endotoxin plus polyethylene glycol-adsorbed-superoxide...
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