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Pasteur Institute of Brussels

Data from Belgium, Japan and the South Africa advance knowledge in tuberculosis research

Published in Law and Health Weekly, August 19th, 2006

Tuberculosis data are the focus of recent research from Belgium, Japan and the South Africa.

Study 1: Partial reconstitution of the CD4+-T-cell compartment in CD4 gene knockout mice restores responses to tuberculosis DNA vaccines.

According to recent research published in the journal Infection and Immunity, "Reactivation tuberculosis (TB) is a serious problem in immunocompromised individuals, especially those with human immunodeficiency virus (HIV) co-infection. The adaptive immune response mediated by CD4+ and CD8+ T cells is known to confer protection against TB. Hence, vaccines against TB are designed to activate these two components of the...

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