Sun Yat-Sen University Hospital, Guangdong, People's Republic of China
Nasopharyngeal cancer cell metastasis inhibited by RNA interference
Published in Law and Health Weekly, October 14th, 2006
"Nasopharyngeal carcinoma (NPC) is a highly metastatic carcinoma characterized by consistent association with EBV. Of the EBV-encoded product, LMP-1 is considered to be an oncoprotein playing an essential role in cell transformation and metastasis.
"In this study, we used a rAAV type 2 vector (rAAV-2) to deliver small hairpin RNA (shRNA) targeting EBV LMP-1 into the...
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