Gene Therapy

Natural product discovery by Cleveland medical researchers blocks tissue destruction

Published in Law and Health Weekly, November 10th, 2007

Scientists at Case Western Reserve University's School of Medicine have published in the Journal of Inflammation a remarkable discovery with a natural product derived from the Amazon rainforest. The discovery's unique actions suggest a broad set of applications in various joint, skin and gastrointestinal diseases, including osteoarthritis and irritable bowel syndrome.

The publication revealed that Progrado®, an extract from a rainforest tree called Croton palanostigma, was a remarkably potent antioxidant and prevented the destruction of human cartilage by molecular s scissors called matrix metalloproteinases (MMPs). According to the researchers, these enzymes cut...

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Source: Law and Health Weekly (2007-11-10)

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