Angiogenesis

EntreMed Announces FDA Acceptance of IND Application for Panzem(R) in Rheumatoid Arthritis

Published in Law and Health Weekly, December 29th, 2007

EntreMed, Inc. (NASDAQ:ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, announced that the U.S. Food and Drug Administration (FDA) has accepted its Investigational New Drug (IND) application for Panzem(R) (2-Methoxyestradiol or 2ME2) in rheumatoid arthritis (RA).

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a proliferating synovium (joint lining), aberrant angiogenesis, and progressive joint damage. Panzem(R) is a small molecule metabolite of 17beta-estradiol which, in its purified form, has antiproliferative, apoptotic, and antiangiogenic activity. These...

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Source: Law and Health Weekly (2007-12-29)

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