Monoclonal Antibodies

Bright lights: Mystery of glowing antibody solved by Scripps research scientists

Published in Law and Health Weekly, March 15th, 2008

Now, a group of Scripps Research scientists have shown that EP2-19G2, one of a panel of fluorescent monoclonal antibodies that were first reported in 2000, produces its distinctive bright blue glow through a rare and highly complex recombination of electrical charge.

This charge recombination involves an electron hole—the gap left by the electron as it is transferred from one molecule to the other.

The new study was published in the February 29, 2008 edition (Volume 319, Number 5867) of the journal Science.

"Our study describes in detail the rare and rather surprising mechanism that creates this exceptionally bright and...

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Source: Law and Health Weekly (2008-03-15)

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