Johns Hopkins Medical Institutions

Johns Hopkins researchers say vaccine appears to 'mop up' leukemia cells Gleevec leaves behind

Published in Law and Health Weekly, January 23rd, 2010

Johns Hopkins Kimmel Cancer Center researchers say preliminary studies show that a vaccine made with leukemia cells may be able to reduce or eliminate the last remaining cancer cells in some chronic myeloid leukemia (CML) patients taking the drug Imatinib mesylate (Gleevec).

Gleevec, one of the first targeted cancer therapies with wide success in CML patients, destroys most leukemic cells in the body, but in most patients, some cancerous cells remain and are measurable with sensitive molecular tests. These remaining cells are a source of relapse, according to the investigators, especially if Gleevec therapy is stopped.

In a pilot study published in...

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Source: Law and Health Weekly (2010-01-23)

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