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Life Science Weekly

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Immunology



Reductions in total body fat decrease humoral immunity



March 31st, 2003

A study in hamsters reveals that total body fat loss leads to impaired immunity,

Dr. Gregory Demas and colleagues at Indiana University reported their findings in the Proceedings of the Royal Society of London, Series B.

Limited energy availability, reflected as reduced body fat, can impair immune function and increase disease susceptibility, noted the authors.

They performed lipectomy on prairie voles and Siberian hamsters.

"In both species, reductions in body fat impaired immunity," reported Demas and colleagues.

"Over time, Siberian hamsters compensated for the loss of fat by...


Source: Life Science Weekly (2003-03-31)

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