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Developmental Biology



VEGF regulates vascular morphogenesis in the Japanese quail embryo



June 23rd, 2003

VEGF regulates vascular morphogenesis in the Japanese quail embryo.

According to published research from the United States, "experiments in mouse embryos indicate that a critical level of VEGF is required for normal vascular development, as mice lacking a single VEGF allele die at midgestation. Thus VEGF concentration may be a determinant of the size and location of major blood vessels during formation of the primary capillary plexus. Ectopic VEGF delivery was used to examine the effect of VEGF concentration on early vascular patterning in the quail embryo."

"VEGF was delivered by implanting VEGF-soaked heparin chromatography beads at three...


Source: Life Science Weekly (2003-06-23)

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