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Susan Hasty, Publisher Table of Contents . . . January 25th, 2005 Non-Subscriber - Summaries Only Related Areas: Other Issues in Life Science Weekly | Other Publications
Complementary & Alternative Medicine - Tinospora cordifolia restores antioxidant function in diabetic organsComplementary & Alternative Medicine - Green tea flavonoid may lower the invasive potential of prostate cancerDiagnostics - Methods to analyze irradiated spicy vegetables describedDrug Development - Medicinal and pharmaceutical uses of seaweed natural products reviewedLipid Studies - Hazelnut oil reduces aortic cholesterol accumulationProteolysis - Xenopus laevis egg envelope hardening studied, role of proteolysis revealedAIDS/HIV Vaccines - New findings in the area of AIDS/HIV vaccines describedAcute Lymphocytic Leukemia - Gene homologous to endogenous retrovirus overexpressed in childhood ALLAcute Lymphocytic Leukemia - Unrelated cord blood transplantation is an option for children with ALLAcute Myelogenous Leukemia - Clinical outcome not affected in pediatric AML patients with PTPN11 mutationsAcute Myeloid Leukemia - 57.9% of elderly acute myeloid leukemia study patients respond to chemotherapyAcute Radiation Syndrome - Biotechnology company responds to U.S. HHS Request for InformationAddiction Medicine - Ghrelin and glucagon-like peptide studied, role of cannabinoids revealedAddiction Medicine - Study in rats finds no connection between anxiety and alcohol useAdenovirus - Antihexon antibody model neutralizes adenovirusAdenovirus - Cidofovir effectively treats adenoviral hemorrhagic cystitis in HSCT patientsAdolescent Health - Study reveals high infection rate in teens for virus linked to cervical cancerAdult T-Cell Leukemia - Adult T-cell leukemia cells down-regulate CD26 antigens via epigenetic machineryAdverse Drug Effect - Statins induce apoptosis in rat and human myotube culturesAdverse Drug Events - Consumer Group: Drug industry volunteer reporting plan falls shortAdverse Drug Events - Doctors must consider potentially inappropriate meds when treating elderlyAdverse Drug Events - Long-term use of NSAIDs causes severe intestinal damageAdverse Drug Events - U.S. FDA gives scientist permission to publish Vioxx safety dataAdverse Drug Reaction - Collaborative to study unanticipated serious adverse drug events using enTRUSTAdverse Drug Reaction - EMEA to review celecoxib studies' resultsAdverse Drug Reaction - Markers implicated in fatal side effects of schizophrenia drug identifiedAdvocacy - AIDS group to call for ban on consumer drug advertisingAging - Activation of AMPK by in vivo hypoxia is slower than in vitroAging - Food intake in elderly rats studied, ineffectiveness of orexin-A revealedAging - Study compared isometric contractions of young and old men and womenAgriculture - Consumers benefit from organic potato breakthroughAir Pollution - Several hazardous air pollutants exceed cancer risk level in PortlandAlcohol Use - Bipolar alcoholics helped by seizure drugAlcohol Use - College attendance influences alcohol drinking patterns in young femalesAlcohol Use - Taurine not involved in pharmacological effects of ethanol in ratsAlginate - Alginate from Sargassum spp obtained and cadmium binding studiedAllergic Contact Dermatitis - Galanin expression characterized in murine modelAllergy & Immunology - Asthma study analysis sends wrong messages, cleaning group saysAllergy & Immunology - Hay fever treatment shown to reduce symptoms by 37%Allergy and Immunology - Thymalfasin augments the immune system's response to diseaseAlzheimer Disease - Healthy cleavage: How statins protect against ADAlzheimer Disease - Method for screening beta-amyloid secretion inhibitors developedAlzheimer Disease - New research in the area of Alzheimer disease detailedAlzheimer Disease - Phosphorylated eukaryotic translation factor 4E heightened in Alzheimer brainAlzheimer Disease - Results of clinical trial of GABA(B) receptor antagonist SGS742 reportedAlzheimer Disease - Scientists develop split green for tagging proteinAlzheimer Disease - Synaptic targeting by AD-related amyloid beta oligomers provide disease cluesAlzheimer Disease - Women bear a double burden with Alzheimer disease, says resource center reportAmyotrophic Lateral Sclerosis - Neuroprotection offered by antibioticsAnal Fissures - U.S. FDA issues not approvable letter for CellegesicAnemia - Anemia prevalent in cancer patients, European Cancer Anaemia Survey showsAnesthesia - Propofol not recommended for long-term sedation of critically illAngiology - Beta arrestin activity studied, need for angiotensin receptor revealedAngiology - Correlates of carotid artery stiffness in young adults reportedAngiology - H2 S produces relaxant response of resistance arteriesAngiology - Mef2c mediates vascular gene expression during endothelial cell developmentAngiology - Physiological roles of angiotensin-converting enzyme 2 reviewedAngiology - Researchers describe findings in angiology studiesAngiology - Structure of angiotensin I-converting enzyme revealedAngiology - Thrombosis and infarction associated with collagen receptor polymorphismAngiology - VEGF isoforms reveal a time-related response to hypoxia in the knee jointAngiology - Vascular smooth muscle viability is pertinent to tumor biologyAngioplasty - 18 New Jersey hospitals seek permission for new heart serviceAnkylosing Spondylitis - U.S. FDA approves REMICADE for patients with ankylosing spondylitisAnthrax - Breakthrough could lead to anthrax antidoteAntibacterial Agents - Bacterial killing studied, dual role of phagocytic NADPH oxidase revealedAntibiotics - Binding of an aminoacridine derivative to a GAAA RNA tetraloop revealedAntifungal Activity - Chitinase from E. coli carrying Streptomyces gene is antifungalAntimicrobials - Antimicrobial and antioxidant activities of medicinal plants reviewedAntimicrobials - Treatment of dialysis catheter-related bacteremia reviewedAntioxidants - Oral antioxidants have mixed effects on UV-induced skin damageAnxiety - Stanford study shows hypnosis helps kids undergoing difficult procedureApoptosis - Apoptosis analyzed, resistance in regenerating hepatocytes demonstratedApoptosis - Fibroblast cell lines derived from LEC rats are highly susceptible to heatApoptosis - Pancreatic hypoplasia studied, induction and influence of nitric oxide revealedApoptosis - Tumor necrosis factor-alpha induces apoptosis in adrenocortical cellsArgemone Oil - Argemone oil is genotoxicArrhythmia - Reductions in Cx43 are associated with increased arrhythmiasArthritis - A key signaling molecule in osteoarthritis is identifiedArthritis - Erythrocyte sedimentation rate adjusted for hematocrit and hemoglobin levelsArthritis - Laser therapy is an alternative to VIOXX for arthritis sufferersArthritis - Renal amyloidosis complicating rheumatoid arthritis treated with etanerceptAspergillus - Intake of rice with Aspergillus and polybrominated diphenylethers studiedAssisted Reproduction - Biopharmaceutical company receives CE Mark for CumulaseAssisted Reproduction - Estradiol and testosterone levels in follicular fluid predict oocyte maturityAssisted Reproduction - Genes expressed during ovarian hyperstimulation may not affect implantationAssisted Reproduction - Growth differentiation factor gene fragments treat porcine ovarian dysfunctionAsthma - S. mansoni -infected asthma patients produce lower levels of Th2 cytokinesAsthma - Indiana health agency plans 5-year attack on asthmaAstrocytoma - Chromosomal aberrations identified in diffuse astrocytomasAstronomy - Scientists observe largest explosion in spaceAtheroscerlosis Risk Factors - Caloric restriction significantly improves insulin sensitivityAtherosclerosis - Atherogenic Western diet enhances intestinal MTP gene expressionAtherosclerosis - COX-2-derived prostacyclin confers atheroprotection on female miceAtherosclerosis - Cholesterol acyltransferase 2 have opposite atherosclerotic potentialAtherosclerosis - HB-EGF can play an integral role in atherogenesisAtherosclerosis - Hepatic lipase can have a variable effect on atherosclerosisAtherosclerosis - Reduced progression of plaques tied to statin drugsAtherosclerosis - Stent-based gene therapies offer a strategic way to treat arterial diseaseAtherosclerosis - Studies add new findings to atherosclerosis body of knowledgeAtopic Dermatitis - EWGAD issues clinical guidance on use of topical calcineurin inhibitorsAtrial Fibrillation - CE Mark clearance granted for the surgical ablation systemAtrial Fibrillation - Clinical trial enrollment announced for radiofrequency ablation technologyAtrial Fibrillation - Dual-chamber pacemakers worth extra cost, study findsAtrial Fibrillation - Study investigated mechanism of atrial dilatation during fibrillationAtrial Fibrillation - Ximelagatran is as effective as warfarin for stroke preventionAutism - Mayo Clinic study suggests no link between autism and immunizationsAutism - Wealthier school systems more likely to diagnose autistic kidsAutoimmune Diseases - Positive results reported in phase I/II trial with HuMax-Inflam/MDX-018Awards - Disease management company wins Best Disease Management Program: Medicare awardAwards - Shanghai chemistry R&D services company recognized for excellence by governmentAwards - WaterHealth inventor receives $50,000 Affymatrix award for potable water deviceAwards - Winners of 2004 Life Science Industry Awards announcedBacteriology - Effect of oxalic acid on bacterial regrowth in drinking water studiedBacteriology - Modeling of therapies targeted at bacterial quorum sensing describedBacteriology - Molecular aspects of Corynebacterium glutamicum urea uptake revealedBacteriology - Polychlorinated biphenyls degraded by newly isolated aerobic bacteriumBacteriology - Secretion of bacterial effectors studied, raft-mediated triggering revealedBacteriology - Spectroscopic quantification of bacteria using neural networks reportedBehavior - Two self-fulfilling prophecies are stronger, and more harmful, than oneBehavioral Medicine - Dietary behavior and the stages of change model reviewedBenzene - Xenobiotic metabolism and mechanism of benzene toxicity reviewedBeryllium Disease - Sensitized people should be monitored for eventual granulomatous disease.Bile Ducts - Ligated bile duct secretion modulated by alpha-1 adrenergic receptor agonistsBiochemistry - Study examined effects of surfactants on acid phosphatase denaturationBiological Therapy - DNA decontamination protocols will enhance the value of cell and gene therapiesBiomarkers - Biomarkers valuable for risk assessment in molecular epidemiology of cancerBiomedical Engineering - Companies sign process development and manufacturing agreement for blood enzymeBiomedical Engineering - Matrix-bound ligand boosts local neovascularizationBiomedical Engineering - Medical device company introduces tapered stem hip systemBiomedical Engineering - Stem cell-focused company targets cardio patients for adult stem cell therapyBiomedical Engineering - Whole genome amplification kit introduced by life sciences high tech companyBiotechnology - Modular protein tolerance to alteration of internal repeats clarifiedBiotechnology - Novel microspheres can reversibly transform into vesiclesBiotechnology - Simultaneous tether extraction stabilizes neutrophil rolling under high stressBioterrorism - Bacterial biomarkers identified by chromatography correlate with Gram stainBirth Defects - January 24-30, 2005 is Folic Acid Awareness WeekBirth Defects - Maternal nutritional status affects fetal risk of developing orofacial cleftBladder Cancer - No association between inorganic arsenic concentration and bladder cancer riskBlood Supply - Blood donations needed for winter monthsBody Composition - Body fat values from anthropometric methods and impedance comparedBone Repair - Hydrolysis treatment improves anionic collagen scaffolds for bone repairBotany - Scientists crack secret PIN controlling plant developmentBovine Spongiform Encephalopathy - Canada, U.S. safeguards provide protection against BSE, USDA official saysBovine Spongiform Encephalopathy - Farm Bureau funds full seat on meat export boardBovine Spongiform Encephalopathy - Mad cow case poses no public health threat, Canadian minister saysBrain Cancer Diagnostics - Wet scanning electron microscopy rapidly diagnoses brain tumorsBrain Injury - Group lauds vehicle safety leadership efforts in 2004Breast Cancer - Adenosine is a breast carcinoma cell mitogenBreast Cancer - Adjuvant HT or chemotherapy choice should be offered to women with ER+ tumorsBreast Cancer - Angiogenic profiles of breast carcinomas expose leukocyte penetrationBreast Cancer - Anti-aromatase coumarin derivative characterizedBreast Cancer - Breast cancer may be uniquely sensitive to inhibitors of PI3K pathwayBreast Cancer - CT laser mammography distributor selected for Czech RepublicBreast Cancer - Chemotherapy and long-term outcome compared between lobular and ductal diseaseBreast Cancer - Drugs induce superinvasive phenotype in breast cancer cellsBreast Cancer - Insulin receptor substrate is involved in mammary tumor metastasisBreast Cancer - Mammograms probably don't cause much more biological damage than hard X-raysBreast Cancer - Mammography archived at Univ. of Pennsylvania Health SystemBreast Cancer - More frequent mammography for women on HRT suggestedBreast Cancer - New findings in breast cancer describedBreast Cancer - New findings in the area of breast cancer describedBreast Cancer - New research in the area of breast cancer detailedBreast Cancer - Pharma company updates breast cancer research results from 2004 symposiumBreast Cancer - RT-PCR detects disseminated epithelial cells in BM of breast cancer patientsBreast Cancer - Radiotherapy, susceptibility may increase risk after childhood Hodgkin diseaseBreast Cancer - Reports describe recent advances in breast cancer researchBreast Cancer - Researchers call for new approach to clinical trials in postgenomic eraBreast Cancer - Statins may have anticarcinogenic effects in older womenBreast Cancer - Studies describe new findings in breast cancer researchBreast Cancer - U.S. FDA clears use of automated scanning system for PathVysion DNABreast Reconstruction - Tissue expander colonization not linked to capsular contractureBronchopulmonary Dysplasia - Survivors of BPD go on to develop chronic airflow obstructionBurkholderia - Patterns of genomic variation in Burkholderia species identifiedBurns - Cement burns may have resulted from insufficient information, warningsBusiness & Finance - Cell based technologies market research study releasedBusiness & Finance - Concurrent Pharmaceuticals changes name, secures $34 million in financingBusiness & Finance - Genelabs gets $1.25M for amendment to DNA amplification technology licenseBusiness & Finance - Guilford completes sale and leaseback; receives $19.4M in net proceedsBusiness & Finance - HIPAA alters pharmaceutical company rep strategyBusiness & Finance - HIV test maker sees Q4 revenue, margin gains; 140% increase in HIV product salesBusiness & Finance - Health insurer donates $100,000 to tsunami relief effortsBusiness & Finance - Institutional pharmacy provider commented on proxy statementBusiness & Finance - Medical software company added to American Stock Exchange, names board membersBusiness & Finance - Medical technology company closes public offering, appoints directorsBusiness & Finance - Microelectronics company receives NASDAQ noncompliance noticeBusiness & Finance - Near-infrared instruments developer announces financingBusiness & Finance - Pain management company provides financial guidance for 2005Business & Finance - Pharma company provides support to relief effort in AsiaBusiness Update - Abbott and Genentech ranked among top 10 pharmaceutical sales forcesBusiness Update - Autologous platelet rich plasma preparation system launchedBusiness Update - Biopharmaceutical firm announces relocationBusiness Update - Biopharmaceutical firm announces result of meetingBusiness Update - Biotech company completes European Mutual Recognition ProcedureBusiness Update - Biotechnology company announces sale and leaseback transactionsBusiness Update - Box Elder County in Utah might sell nursing homeBusiness Update - Catholic health systems plan to integrate laboratory servicesBusiness Update - Children's hospital enters agreement for blood pressure monitoring technologyBusiness Update - Company announces favorable rulings in stent patent infringement caseBusiness Update - Company expands mite rearing, processing facilityBusiness Update - Contract research organization signs agreement for clinical monitoring servicesBusiness Update - Cosmetic dentistry laboratory launches new Web siteBusiness Update - DENTSPLY acquires a compound for protection of tooth structureBusiness Update - Device firm announces phase II of its productivity initiativeBusiness Update - Disintegrator needle-destruction device commences global distributionBusiness Update - Fixed-site laser vision correction services provider opens Utah centerBusiness Update - ForHealth Technologies transitions manufacturing of IntelliFill i.v.Business Update - Four Rivers Software announces six distribution partnersBusiness Update - Generic pharmaceutical company announces filing of ANDA with U.S. FDABusiness Update - GeoPharma shares launch strategy for MucotrolBusiness Update - Gordian wins 22 contracts in 6 monthsBusiness Update - Government services provider awarded pharmacy services contractBusiness Update - Growers planting Pioneer brand Sorghum Hybrids win 10 categories in NGSP contestBusiness Update - HealthSouth signs settlement agreement regarding Medicare billing practicesBusiness Update - Healthy foods company introduces new CEO, discusses growth plans in 2005Business Update - Horizon Health leases Laurelwood Hospital of OhioBusiness Update - ICL Fertilizer to change sources of phosphate rock to improve profitabilityBusiness Update - IDX Carecast earns second SCP certificationBusiness Update - IPC-The Hospitalist Company expands practice into North CarolinaBusiness Update - Light-based devices manufacturer announced 150th shipment of LumenisBusiness Update - Medical device company consolidates manufacturing capabilitiesBusiness Update - Medical devices component provider extends agreement with St. Jude Medical, Inc.Business Update - Medical heart-assist device company announces status of U.S. SEC filingBusiness Update - Nashville selects provider for Public Access Defibrillation programBusiness Update - Natural skin care products company begins manufacturing core offerings in CanadaBusiness Update - Nonprofit hospitals in Brownsville, Pennsylvania, weigh in on hospital proposalBusiness Update - Norak Biosciences changes nameBusiness Update - Orthopedic device company signs 3-year contract with hospital supply groupBusiness Update - PROCLEIX ULTRIO Assay approved for use with PROCLEIX TIGRIS SystemBusiness Update - Patient services company consolidates corporate officesBusiness Update - Pharma firm to divest its plasma products business to U.S. investorsBusiness Update - Pharmaceutical firm adopts renewed shareholder rights planBusiness Update - Pharmaceutical group selects software company's quality management systemBusiness Update - Report shows high-content screening market not dominated by any one companyBusiness Update - Reports indicate Bristol-Myers may sell its consumer drug lineBusiness Update - Research on CO2 flux system presented at conferenceBusiness Update - State approves expansion of south Georgia hospitalBusiness Update - Subsidiary granted marketing rights for NeovastatBusiness Update - Technology company awarded five contracts for mental health management servicesBusiness Update - U.S. EPA to use chemogenomics platform to predict potential chemical toxicityBusiness Update - Weight loss clinic opens in TexasBusiness and Finance - White paper issued on measuring accountability of hospital marketingCadmium Exposure - Increased cadmium exposure may influence occurrence of diseaseCancer Genetics - Loss of BRCA1 function associated with sensitivity to DNA-damaging chemotherapyCancer Genetics - Recent findings in cancer genetics provide new insightsCancer Risk - Elevated glucose levels and diabetes associated with risk for cancerCancer Surgery - Complications of free flap head and neck reconstruction reviewedCancer Survival - Reduced health care access and ability to pay decrease cancer survivalCancer Therapy - Additional information provided to U.S. FTC for melanoma treatmentCancer Therapy - Angiogenesis inhibitors antagonize lymphoma proliferationCancer Therapy - Breast cancer patients boost quality of life with vaginal moisturizerCancer Therapy - Brochures help cancer patients make informed treatment decisionsCancer Therapy - Cancer coalition donates medical goodsCancer Therapy - Clolar wins FDA approval for common pediatric leukemiaCancer Therapy - Data on successful treatments for lymphoma with few side effects presentedCancer Therapy - Free makeovers at Alabama hospital boost spirits of cancer patientsCancer Therapy - IND filed with U.S. FDA for AP5346Cancer Therapy - Imaging study of dogs offers insight into 9/11 resulting cancersCancer Therapy - New treatment for cancer of the larynx at available at medical centerCancer Therapy - Protein arginine methyltransferase complexes regulate tumor suppressor genesCancer Therapy - Quinolones enhance antitumor activity of ultrasonic irradiationCancer Therapy - Research in cancer therapy provides new insightsCancer Therapy - Researchers detail new studies and findings in the area of cancer therapyCancer Therapy - Researchers publish new studies and findings in the area of cancer therapyCancer Therapy - Residual tumor cells are a barrier to targeted cancer therapeuticsCancer Therapy - Study examines target for blocking new lymphatic growthCancer Therapy - Trial: IRESSA failed to significantly prolong survival in comparison to placeboCancer Therapy - Tumor cells resistant to hemiasterlin analogue characterizedCancer Vaccines - Biopharmaceutical company announces survival data of trial with cancer vaccineCancer Vaccines - Findings advance knowledge in cancer vaccines researchCancer Vaccines - Reports add new data to cancer vaccines researchCancer Vaccines - Researchers' findings advance cancer vaccines researchCancer Vaccines - Studies add new findings to cancer vaccines body of knowledgeCancer Vaccines - Studies advance knowledge in cancer vaccines researchCandidemia - Antifungal medicine VFEND receives U.S. FDA approval for blood infectionCandidiasis - CaMIT1 inactivation reduces Candida albicans virulenceCarcinogenesis - Reports describe recent advances in carcinogenesis researchCardiology - "Annexin A5 resistance" is a mechanism for thrombosis in aPL syndromeCardiology - TrxR2 plays a pivotal role in both hematopoiesis and heart functionCardiology - Anatomic factors influence slow pathway conductionCardiology - Compensated hypertrophy is associated w/ preserved myocardial functionCardiology - Early aortic remodeling in hypertensive rats may have genetic originsCardiology - Effects of junctin overexpression on Ca2+ vary with ageCardiology - Endogenous inhibitory factor NCXIF is a reasonably potent blockerCardiology - Findings describe new data in cardiology researchCardiology - Findings in cardiology provide new insightsCardiology - Incubation of aorta produces reduction in agonist-evoked contractionCardiology - Mechanisms of reduced cardiac function after brain death are reviewedCardiology - Model reproduces experimental results for Ca2+ handling in myocytesCardiology - New data illuminates research in cardiologyCardiology - New findings in the area of cardiology describedCardiology - New research in the area of cardiology detailedCardiology - Oxidative stress plays a role in clomipramine-induced cardiotoxicityCardiology - Postprocedural creatinine increase was a predictor of late mortalityCardiology - Preconditioned hearts may inhibit F0 1 ATP synthase activityCardiology - Report describes perioperative diagnosis of cardiac risk patientsCardiology - Researchers detail new studies and findings in the area of cardiologyCardiology - Researchers provide details of new studies and findings in the area of cardiologyCardiology - ST-segment depression is associated with the magnitude of ischemiaCardiology - Structures may elucidate mechanisms of volvatoxin A2 and Cyt toxinsCardiology - Study fails to demonstrate myocardial protective effects of clevidipineCardiology - Study investigated PKC isoforms in ischemic preconditioningCardiology - Study tested whether treatment with tedisamil affects cardiac growthCardiology - Superoxide dismutase protected endothelium in ischemia-reperfusionCardiology - Synaptic dysfunction may be an early marker for neuronal cell deathCardiology - Tirofiban reduced the risk for death, MI, and refractory ischemiaCardiology - Transplanted bone marrow cells generate angiogenic factors in the heartCardiomyopathy - Medical device company announces results of study in hypertrophic cardiomyopathyCardioprotection - Cardioprotection of erythropoietin is linked with apoptosis inhibitionCardioprotection - Report describes mechanisms of cardioprotection afforded by K/Mg + DZXCardiopulmonary Bypass - Miniaturized extracorporeal circulation system reduces morbidityCardiopulmonary Bypass - Surgeon can test occlude to identify vessel to be ligatedCardiovascualr Research - Hyperosmolality regulates atrial myocytic ANP releaseCardiovascular Disease - Complication risk with coronary catheterization low in moderate obesityCardiovascular Disease - Position article on cardiac surgery risk models releasedCardiovascular Research - Ang II-mediated pressor responses are mediated via V1 receptorsCardiovascular Research - Decrease in preload during recovery may be prevented by CV mechanismsCardiovascular Research - Genetic background affects features of breathing during sleepCardiovascular Research - H+ stimulates acid-sensing ion channels to evoke reflex responseCardiovascular Research - Heliox breathing improves high-intensity exercise endurance capacityCardiovascular Research - Higher BP was associated with high risk of severe white matter lesionsCardiovascular Research - Increased BP suggests increased vascular resistance during feedingCardiovascular Research - Losartan effects on fetal CV regulation differ by brain regionCardiovascular Research - Midodrine improves the recovery of beat-to-beat BP after exerciseCardiovascular Research - Ouabain and Na pump interact in the caveolar domainCardiovascular Research - Pioglitazone attenuates collagen type I synthesis in fibroblastsCardiovascular Research - Stress response is induced by decompression sicknessCardiovascular Research - Study investigated effects of hyperhomocysteinemiaCardiovascular Research - Study investigated muscle sympathetic nerves during orthostatic stressCardiovascular Research - Study investigated selective muscle mechanoreceptor activationCardiovascular Research - Study supports evidence of gating-induced changes in Phe656 side chainsCarotid Artery Disease - Pros, cons of endarterectomy considered in women with symptomatic ICA stenosisCarpal Tunnel Syndrome - Workers with repetitive-motion problem find relief with night-time splintingCartilage Repair - Biphasic scaffold developed for cartilage tissue engineeringCation Transporter - Organic cation transporter hOCT1 analyzed, regulation revealedCell Biology - Binding site for antimitotic peptides identified on beta-tubulinCell Biology - Interferon-gamma and interferon-alpha have opposing effects on stellate cellsCell Biology - Proteomic gate-keepers regulate the outcomes of senescent cellsCell Biology - Research yields cellular snapshot of protein fluxCell Biology - Researchers discover how serum factors prevent TRAIL-induced apoptosisCell Biology - Researchers tease out one critical role of tumor-suppressor geneCell Biology - Study of hypoxia and new gene reveals early-stage action of p53 geneCell Biology - VEGF increases the availability of channels used for paracellular transportCell Differentiation - Claudin localization is regulated in developing by fetal alveolar epitheliaCell Research - C-terminally truncated Cx43K258stop mice lack functions of Cx43Cell Research - E2F-1 is a potential target in treatment of myoblast hypertrophyCell Research - Model predicts that cell growth rate relates to surface area at birthCell Research - Results suggest dimerization mechanism for mitochondrial ATP synthaseCell Research - Study investigated fluctuations in mitochondrial membrane potentialCerebrovascular Disease - Genes delivered following cerebral infarction improve neurological outcomesCerebrovascular Disease - Homeobox D3 gene delivery initiates cerebral angiogenesis in miceCervical Cancer - Exposure to secondhand smoke increases risk of developing cervical tumorsCervical Cancer - January 2005 is Cervical Cancer Screening MonthCervical Cancer - Recent studies add new data to cervical cancer researchCervical Cancer - Reports advance knowledge in cervical cancer researchChagas Disease - Trypanosoma cruzi gene structure does not sway drug susceptibilityChlamydia - Candidate NAD+ transporter in bacterial symbiont identifiedChlamydia trachomatis - Hematopoietic cells needed to initiate specific CD8+ T-cell responseCholesterol - Cholesterol drug co-administered with fenofibrate study results reportedCholesterol - Other lipids besides LDL-C influence cardiovascular healthChromatin - Condensation of chromatin studied, role of cations clarifiedChronic Liver Disease - Angiotensin II receptor antagonist treats nonalcoholic steatohepatitisChronic Pain - U.S. FDA approves ziconotide intrathecal infusion for severe chronic painCirrhosis - Research offers hope of new treatments for liver damage "plague"Climate Change - Antarctic iced over because of greenhouse gases - not ocean currentsClinical Trails - Phase II trial of HyCAMPTM initiated for colorectal cancerClinical Trials - Company provides update on cancer and HIV clinical-development programsClinical Trials - DATATRAK to provide technology solutions for clinical trialsClinical Trials - Race may influence the response to recombinant HIV-1 gp120 vaccinesClinical Trials - Results of autoimmune therapy in healthy volunteers study releasedClinical Trials - Synthetic antibodies manufacturer announces phase 1 trialCoagulation - Coagulation factor Va analyzed, enhanced cleavage by protein C revealedCochlea - Noise perception of mice analyzed, role of spiral ganglion responses revealedCollaborations - ActiveHealth Management works with Aetna on chronic care programCollaborations - Agreement signed for transdermal treatment for major depressive disorderCollaborations - Alliance formed for Canvaxin for melanomaCollaborations - Blue Cross Blue Shield of Georgia joins Anthem Blue Cross and Blue ShieldCollaborations - Companies agree to terminate dormant joint ventureCollaborations - Companies to commercialize INTERCEPT system for plasma in Asian regionCollaborations - Deal signed for development of osteoporosis and bone loss therapyCollaborations - Device company forms partnership with TDC MedicalCollaborations - Device firm strengthens presence in Southeast Asia, ChinaCollaborations - Discovery program launched to combine antibody technologiesCollaborations - Drug discovery company announces collaborationsCollaborations - GPC Biotech announces achievement of milestones totaling $1.2MCollaborations - Joint venture formed to develop fixed-dose combination of three HIV medicinesCollaborations - Library deal signed with Sanofi-Synthelabo RechercheCollaborations - Neugene antisense deal signed with Walter Reed Army Institute of ResearchCollaborations - New anti-angiogenesis program added to collaborative agreementCollaborations - Pharmaceutical firm acquires exclusive rights to NordetteCollaborations - Pharmaceutical firm signs supply agreement with Ceph InternationalCollaborations - Pharmaceutical firms team up to develop diabetes treatmentsCollaborations - Research alliance formed to develop compounds for metabolic diseaseCollaborations - Supplier agreement signed with Bausch & Lomb for viscoelastic productsCollaborations - Trisenox financing agreement signedColon Cancer - Breakthrough cancer treatment Avastin approved in SwitzerlandColon Cancer - CHOP regulates ER stress-induced apoptosis by enhancing DR5 expressionColon Cancer - Integrated therapies show promise for treating colorectal cancerColon Cancer - Long-term consumption of red and processed meat linked with cancer riskColon Cancer - System detects colon polyps in colons previously obscured by fluidColorectal Cancer - APAF-1 gene dysfunction from allelic imbalance increases with tumor progressionColorectal Cancer - Colorectal cancer detected by quantitative fluorescence of stool DNAColorectal Cancer - Data advance knowledge in colorectal cancer researchColorectal Cancer - HNPCC predictive genetic testing does not cause adverse psychological outcomesColorectal Cancer - High dietary intake of magnesium may help reduce women's riskComplementary & Alternative Medicine - Chamomile tea: New evidence supports health benefitsComplementary & Alternative Medicine - HealthSaver offers discounts on alternative health care productsComplementary & Alternative Medicine - Natural tea supplement viable option for slowing Alzheimer diseaseComplementary & Alternative Medicine - Research shows omega-3 fats feed the human brain, not the hipsCongestive Heart Failure - Collaboration to develop AAV-based gene therapies for congestive heart failureCongestive Heart Failure - First U.S. implantation of a biventricular pacemaker for the AVAIL CLS/CRT studyCongestive Heart Failure - Heart failure registry shows differences in Hispanic Americans' health statusCongestive Heart Failure - Study pinpoints protein's role in heart failure preventionContraception - Getting pregnant while on the pill: another health hazard of being overweightCoronary Artery Disease - Trial to evaluate skin sterol values and new coronary artery disease markersCoronary Heart Disease - Middle-aged women with relatively high heme iron intake have increased CHD riskCoronary Heart Disease - Report: Catheters set to play an expanding role in interventional cardiologyCorrection - Medifast to purchase Xerox's DocuColor iGen3 Digital Production PressCorrectional Health - Inmate infections spreading, officials warn of public health riskCorrectional Health - Many Minnesota state prisoners have "meth mouth"Cosmetic Surgery - Clear Channel criticized over contest that granted breast surgeryCosmetic Surgery - Cosmetic procedures are gaining popularity among menCritical Care Medicine - Bonfils fiberscope effective for management of difficult intubationCritical Care Medicine - Laryngeal tube insertion not feasible during manual in-line neck stabilizationCritical Care Medicine - Microbial keratitis may be occupational hazard for ITU staffCrohn's Disease - Serum and local levels of sRANKL and OPG are increased in CDCrosslinking - Carbodiimide-crosslinked HA/collagen membrane safe and effective antiadhesiveCryptosporidium - Cyclospora oocysts are not ingested by the nematode Caenorhabditis elegans Cystectomy - Robotic radical cystectomy for managing bladder cancer reviewedCystic Fibrosis - Airway prostasin is therapeutic target in cystic fibrosisCystic Fibrosis - Biopharma company announces phase 1 study for PTC124Cystic Fibrosis - Golf tournament raises money for cystic fibrosis foundationCystic Fibrosis - Results help to interpret nasal potential differences in animal modelsCytomegalovirus - Initiation of HCMV lytic replication involves transcriptional activationCytoplasmic Body Myopathy - Cytoplasmic body myopathy analyzed, similarity to motor neuron disease revealedDNA - DNA molecules have increased binding affinity for human prourokinaseDNA Research - Mitochondrial transcription factor A maintains human mitochondrial DNADNA Research - Novel bleomycin conjugates cleave double-stranded DNADNA Research - Processive DNA methylation occurs preferentially at hemimethylated target sitesDNA Research - Telomere damage and shortening rate in fibroblasts reduced by L-carnosineDNA Transcription - RNA polymerase mutant deficient in DNA melting useful in study of activationDairy Science - Skeletal tissue growth rates increased in prepubertal dairy heifersDefibrillation - Virtual electrodes do not explain mechanism of defibrillationDementia - Weight loss may be an early sign of dementia in the elderlyDepression - Doctor's death calls attention to depressionDepression - European drug review group meets on paroxetine and other SSRIsDepression - U.S. FDA grants ANDA for generic citalopram hydrobromide tablets for depressionDermatology - Antikeratin monoclonal antibody generatedDermatology - Communications provider invests in beautyDermatology - Company receives CE Mark for new cosmetic dermal fillerDermatology - Genetic characterization of epidermolysis bullosa should improve diagnosesDermatology - Genomic response to asiaticoside in fibroblasts clarifiedDermatology - Keratinocyte growth and differentiation factors guide drug investigationDermatology - Non-healing ulcers signal the possibility of factor V Leiden mutationDermatology - Non-viral gene therapy may help patients with skin disordersDermatology - Novel keratinocyte protein linked to wound healingDermatology - Phase II trial of AVAC fails to meet the primary efficacy endpointDermatology - Researchers' work adds to dermatology body of knowledgeDermatology - Semaphorin 3F prohibits melanoma metastasisDevelopmental Biology - Zebrafish may hold key to understanding human nerve cell developmentDiabetes Complications - Lipid lowering agents may reduce the risk for diabetes-related vision lossDiabetes Complications - No blind mice, thanks to stem cell scientistsDiabetes Complications - Pancreatic islets from type 2 diabetic patients have functional defectsDiabetes Complications - TNF-alpha release negatively associated with apolipoprotein BDiabetes Genomics and Genetics - Biethnic comparisons of autosomal genomic scan for loci linked to adiponectinDiabetes Genomics and Genetics - Insulin-like growth factor-II receptor gene linked to type 1 diabetesDiabetes Genomics and Genetics - Lymphoid tyrosine phosphatase locus associated with type 1 diabetesDiabetes Genomics and Genetics - Mutations in KCNJ11 gene rare in type 1 diabetes diagnosed before 2 yearsDiabetes Genomics and Genetics - Protein tyrosine phosphatase polymorphisms linked to glucose homeostasisDiabetes Genomics and Genetics - Variation in NCB50R does not contribute to nonautoimmune diabetesDiabetes Pathogenesis - Biological importance of peptides of calcitonin family examinedDiabetes Pathogenesis - Fas deficiency prevents type 1 diabetes via T-cell hyporesponsivenessDiabetes Pathogenesis - Findings describe new data in diabetes pathogenesis researchDiabetes Pathogenesis - Hyperglycemia induces vagally mediated increase in C-peptide secretionDiabetes Pathogenesis - PPAR-gamma overexpression suppresses insulin secretory capacity in isletsDiabetes Pathogenesis - Phosphatidylinositol 3-kinase inhibitors reveal enhanced insulin secretionDiabetes Pathogenesis - Platelet-derived growth factor stimulates glucose transport in musclesDiabetes Pathogenesis - Research in diabetes pathogenesis provides new insightsDiabetes Pathogenesis - Researchers publish new studies and findings in the area of diabetes pathogenesisDiabetes Pathogenesis - Serine phosphorylation promotes insulin resistanceDiabetes Pathogenesis - Studies advance knowledge in diabetes pathogenesis researchDiabetes Research - Agreement signed to secure embryonic stem cell technology for diabetes researchDiabetes Risk Factors - Gamma-glutamyltransferase predicts risk of type 2 diabetesDiabetes Therapy - Activated protein C preserves islet mass after intraportal transplantationDiabetes Therapy - Affinity chromatography of insulin with heptapeptide ligand reportedDiabetes Therapy - Amylase inhibitor from kidney beans has hypoglycemic activityDiabetes Therapy - Dual-wave bolus feature in insulin pumps better at controlling hyperglycemiaDiabetes Therapy - Free radical scavenger protects against glucose-induced cell dysfunctionDiabetes Therapy - Glibenclamide treatment effective in permanent neonatal diabetesDiabetes Therapy - Glycoinsulins possess prolonged blood-sugar-lowering activityDiabetes Therapy - Mitochondrial dysfunction by synthetic PPAR ligands reviewedDiabetes Therapy - New findings in diabetes therapy describedDiabetes Therapy - Phloridzin improves hyperglycemia but not hepatic insulin resistanceDiabetes Therapy - Pioglitazone restores impaired glucose-stimulated insulin secretionDiabetes Therapy - Proteins released by islets affect islet engraftment in type 1 diabetesDiabetes Therapy - Reports describe recent advances in diabetes therapy researchDiabetes Therapy - Severe hypo-alpha-lipoproteinemia reported during rosiglitazone therapyDiabetes Therapy - Short gastric veins unsuitable for pancreatic islet transplantationDiabetes Therapy - Simvastatin restores vasoconstriction via effects on oxidizing metabolismDiabetes Therapy - Synthetic polymer stimulates insulin release from RINm5F insulinoma cellsDiabetes Type 2 Complications - Obesity and metabolic syndrome powerful predictors of diabetes type 2Diabetic Ketoacidosis - Transcriptome and proteome expression in activated T lymphocytes describedDiabetic Nephropathy - Kidneys from nonobese diabetic mice analyzed in non-diabetic stageDiabetic Nephropathy - New findings in the area of diabetic nephropathy detailedDiabetic Neuropathy - Alpha-lipoic acid provides neuroprotection in diabetic ratsDiabetic Neuropathy - Hyperglycemia attenuates nerve conduction velocity in male ratsDiabetic Neuropathy - Venlafaxine provides complete pain relief in acute diabetic neuropathyDiabetic Retinopathy - Combined risk factors accelerate vision complications in diabeticsDiagnostics - Anemia self-screening kit now availableDiagnostics - Antimicrobial exposure suitable for diagnosis of surgical site infectionsDiagnostics - Catholic University in Rome receives CTLM systemDiagnostics - Company chosen to launch thyroid disease detection deviceDiagnostics - Delphi Medical will manufacture vision-testing equipmentDiagnostics - Diagnosis and monitoring of syncope reviewedDiagnostics - FDA 510(k) clearance granted for BioZ DxDiagnostics - Fluorescent ligation detection assay identifies leukemia translocationsDiagnostics - Hair analysis divulges the ingestion of toxic weight loss productsDiagnostics - Homogeneous competitive-type immunoassay for insulin developedDiagnostics - Microarray system cleared by U.S. FDADiagnostics - Neural networks used as statistical tools in epidemiological studiesDiagnostics - Niris System receives market clearance from U.S. FDADiagnostics - Photoswitchable cyan fluorescent protein developed for protein trackingDiagnostics - Radiation sensitivity of Aspergillus flavus in beef jerky reportedDiagnostics - Tandem-repeated DNA probe based amplification simplifies gene detectionDiagnostics - U.S. FDA clears standalone APTIMA test to detect chlamydia trachomatisDiagnostics - Universal procedure exposes DNA and RNA targets in whole bloodDialysis - Dialysis company inks contract in RomaniaDiet & Nutrition - Clinical trials planned for new dietary supplement candidatesDiet & Nutrition - Company ships natural diet products to GNC for 2005 diet seasonDiet & Nutrition - Diets higher in dairy, fruits, and vegetables may address pediatric hypertensionDiet & Nutrition - Don't count on vitamin C to boost your exercise performanceDiet & Nutrition - Elementary school awarded 3-A-Day of Dairy Nutrition Education GrantDiet & Nutrition - How much water is enough during exercise?Diet & Nutrition - Magazine names Seattle fittest city; Houston fattestDiet & Nutrition - Man who lost more than 450 pounds scheduled to go homeDiet & Nutrition - New Hanover schools to end fried foods, serve healthier lunchesDiet & Nutrition - New ebook discusses alternative therapy to reverse chronic diseaseDiet & Nutrition - Research forecasts low-carbohydrate market surge in first quarter of 2005Diet & Nutrition - Survey shows New Year's resolutions focus on wellness over weight lossDiet & Nutrition - Survey shows adults face obstacles in getting nutritious, good-tasting mealsDiet & Nutrition - Survey shows women are striving for balance in their dietDiet & Nutrition - Univ. of Massachusetts study aims at keeping middle school students slimDiet & Nutritoin - Weight loss strategies work in people with prediabetesDiet and Nutrition - Dietary fiber from barley possesses anti-mutagenic activityDiet and Nutrition - Mechanism of olive oil's protective effect against breast cancer determinedDiet and Nutrition - Plasma glucose doesn't alter food restriction-induced hepatic gene expressionDiet and Nutrition - Review finds slim data on diet plansDiet and Nutrition - Study finds eating fruits, vegetables doesn't reduce breast cancer riskDiphtheria - Proteins required for biosynthesis of diphthamide identifiedDisaster Relief - Catholic Healthcare West contributes $250,000 to tsunami reliefDisaster Relief - Company donates water purification tablets for earthquake/tsunami disasterDisaster Relief - Nonprofit supplier sends medical emergency kits to disaster areas in AsiaDisaster Relief - U.S. HHS to lead emergency public health, medical response for major disastersDisease Associations - CRP levels appear only marginally associated with dietary, lifestyle factorsDisease Associations - Hypothyroidism is common in Turner syndromeDomestic Violence - Prevalence among pregnant women found higher upon midwife enquiryDown Syndrome - Physicians often fall short when delivering diagnosis, mothers reportDown Syndrome - Synaptic structural abnormalities identified in murine modelDrug Delivery - 6-Ketocholestanol improves skin permeation of 5-aminolevulinic acidDrug Delivery - Characteristics of water-soluble phospholipid polymer hydrogels describedDrug Delivery - Glucose-targeted niosomes may deliver VIP to brainDrug Delivery - Needle-free injection device made for use with insulin in IndiaDrug Delivery - Sweet basil essential oils enhance transdermal drug deliveryDrug Development - Emblica officinalis extract reduces DMBA genotoxicity in miceDrug Development - Animal study results point to ATL1102's potential as an inhaled asthma drugDrug Development - AstraZeneca withdraws application to market lung cancer drugDrug Development - Biophosphonates for bone metastases pain is potentially lucrative marketDrug Development - Cardiome's pivotal AF study achieves primary endpointDrug Development - Chemical microarray identifies FVIIa-binding compoundsDrug Development - Companies enter partnership to commercialize functional human protein arraysDrug Development - Company launches the HCS Reader 2004 UpgradeDrug Development - Company provides EVOscreen to Institut Pasteur KoreaDrug Development - EU expands approval of Advate for use in children with hemophilia ADrug Development - Effects of novel anxiolytic AF-5 on monoamine neurotransmitters determinedDrug Development - Executives meet in Baltimore to discuss region's biotechnology growthDrug Development - FDA grants approval for Enjuvia for vasomotor symptomsDrug Development - First patient enrolled into phase II trial of Phenoptin for PKUDrug Development - Genetic modifications increase antibiotic yields from microbesDrug Development - Genetically engineered animals in drug development reviewedDrug Development - Innovative R&D strategies are key to developing new drugs, according to studyDrug Development - Investigational new drug application submitted for cancer candidateDrug Development - Ion exchange membranes capture vector-borne virusDrug Development - Meeting with U.S. FDA completed for amoxicillin Pulsys phase III trialDrug Development - Molecular diversity management schemes for compound screening outlinedDrug Development - NDA for Retaane submitted to U.S., European regulatory authoritiesDrug Development - Novel centrally acting thyrotropin-releasing hormone analogues designedDrug Development - Novel docetaxel analogues with high tubulin activity synthesizedDrug Development - Optimized freeze-drying keeps nonviral vectors stable during storageDrug Development - Pharma company licenses Ingenuity Pathways Analysis applicationDrug Development - Pharmaceutical company announces collaboration plans on NRP104Drug Development - Pharmaceuticals company presents data on potency of antifungal, antibiotic drugsDrug Development - Pharmacokinetics, safety, and tolerability of Oritavancin analyzedDrug Development - Reactivation of beta-galactosidase by glutathione is tunableDrug Development - Results reported from phase III study of alvimopan for postoperative ileusDrug Development - Third performance milestone in Genentech Alliance announcedDrug Fatalities - Prescription drug deaths skyrocket in Virginia's coal regionDrug Importation - Canada considering ban of Internet pharmacy prescription drug tradeDrug Importation - Savings from purchasing drugs from Canada fell last yearDrug Importation - Trade group speaks out on drug supply chain safetyDrug Importation - Two governors complain to President Bush about Canadian drugsDrug Research - Prospective allometric scaling is suboptimal for estimating clearanceDrug Resistance - ABC transporters have multiple functions in drug resistanceDrug Resistance - CDC issues public reminder about proper antibiotic useDrug Resistance - Curcumin I most effective multidrug resistance modulator among curcuminoidsDrug Resistance - Genetic resistance to nevirapine emerging in pregnant HIV+ womenEarth Science - Outer layers of Earth contain solids heavily irradiated by solar ionsEating Disorders - Core beliefs of eating disordered patients with anxiety need to be identifiedEating Disorders - Endorphin self-addictive model may apply to eating disordersEating Disorders - New data illuminates research in eating disordersElectronic Medical Records - Companies compete in Medical Record Institute's ePrescribing challengeElectronic Medical Records - Medical database provider upgrades to meet JCAHO patient safety compliance goalsElectrophoresis - Novel PDMS microchip has improved heat dissipationEmbryonal Brain Tumor - Notch1 and Notch2 can have opposite effects on single tumor type growthEmbryonic Stem Cell Research - Cryopreservation technique increases ESC viability and reduces differentiationEmbryonic Stem Cell Research - ESC gene profiles show more highly expressed genes than adult cellsEmergency Contraception - Study: Readily available EC doesn't increase unprotected intercourse, STI riskEmergency Contraception - U.S. ob/gyn group: Study findings put spotlight on controversial FDA OTC rulingEmergency Medicine - Insulin treatment in critically ill trauma patients normalizes glucoseEndocarditis - Elevated troponin I may be a reflection of myocardial involvementEndocrinology - Activation of nuclear factor by hyperglycemia regulated by aldose reductaseEndocrinology - Affect of exogenous progestagens on the human breast remains controversialEndocrinology - Cofilin suppresses glucocorticoid receptor activity in hormone-resistant cellsEndocrinology - Diabetes in pregnancy appears to imprint glucocorticoid regulation in fetusEndocrinology - Expression of mini-proinsulin in Pichia pastoris improvedEndocrinology - GnRHA, TGF-beta influence fibronectin expression in endometrial cellsEndocrinology - Growth hormone prompts endocrine or paracrine activity during spermatogenesisEndocrinology - Insulin acts via protein kinase phosphorylation in blastocystsEndocrinology - Link found between mitochondrial efficiency and insulin resistanceEndocrinology - Microenvironmental factors guide glucocorticoid influence in the thymusEndocrinology - Novel microbead system facilitates isolation of specialized cell typesEndocrinology - Scientists identified role of genes in corpus cardiacum morphogenesisEndocrinology - Sesame lignans augment vitamin E activity in lipid peroxidation systemsEndocrinology - Specific hormone and growth factor mediated activation revealedEndoplasmic Reticulum - Varied activation of endoplasmic reticulum stress-responsive elements revealedEnvironmental Health - Cleveland, Ohio, combats childhood lead poisoningEnvironmental Health - Component of plastic stimulates growth of certain prostate cancer cellsEnvironmental Health - Enzyme immunoassay developed for detection of AOZ in prawn tissueEnvironmental Health - People exposed to asbestos show early signs of autoimmunityEnvironmental Health - Secondhand smoke linked to cognitive declines in childrenEnvironmental Health - Synthetic musks may enhance the effects of toxic compoundsEnvironmental Health - U.S. NIST/EPA study aims at healthy indoor climateEnvironmental Health - Validity of a food-frequency questionnaire reported and verifiedEnvironmental Health - Waste minimization plans affect U.S. medical waste managementEnzymology - Aldoxime dehydratase studied, residues needed in triple bond synthesis revealedEnzymology - Cyclooxygenase-2 studied, expression in H4 human neuroglioma cells revealedEnzymology - Expression level of GGPS is regulated through splicing of intron 4bEnzymology - Matrix metalloproteinases govern capillary tube formation differentiallyEnzymology - Metal ions direct prostasin activityEnzymology - Researchers' work adds to enzymology body of knowledgeEnzymology - Residues in factor Xa critical to interaction with Na+ , factor VaEnzymology - Sp1 mediates lysozyme activation in epithelial cellsEnzymology - Two-step activation manages gene expression in skeletal musclesEpidemiology - Hepatitis E virus common among pregnant women in small study from IndiaEpidemiology - Molecular studies predict higher rates of liver cancer in the United StatesEpidemiology - Results of HIV prevalence survey among general population in Niger releasedEpidermal Growth Factor - Esophageal keratinocyte migration studied, role of signaling pathway revealedEpilepsy - Chronic epilepsy decreases brain cell production in critical learning centerEpilepsy - Clonazepam may use alternate control routes in genetic absence epilepsy ratsEpilepsy - New clues to the genetics of epilepsyErythropoiesis - CPEC induces erythroid differentiation through CTP depletion and p38 MAP kinaseEscherichia Coli - E. coli metabolism studied, role of transcription factor revealedEscherichia Coli - Ozone treatment alternative to pasteurizationEscherichia coli - High incidence of ESBLs among outpatient clinical E. coli isolatesEsophageal Variceal Bleeding - FDA issues approvable letter for Sanvar for esophageal variceal bleedingEstrogen - Estradiol-induced induction does not require direct MAPK/ERK activationEthics - NIH whistleblower says government bungled AIDS study in UgandaEthics - Study describes physicians' response to religious conflicts in medicineEvolutionary Biology - Great tits show how differences can flourishEvolutionary Biology - Holes in fossil shells show effects of competition and evolutionFetal Medicine - New system may help babies avoid brain damageFinance - ASP closes private placementFinance - Agriculture produces company announces dividendFinance - Antibody-focused biopharmeceutical company reports Q03 2004 financial resultsFinance - Baby products manufacturer announces financial resultsFinance - Biopharma focused on oral drug delivery secures $20M equity commitmentFinance - Biotech firm increases financing to $12,570,000Finance - Biotherapeutic company announces financial resultsFinance - Cancer-focused biopharmaceutical company files registration for proposed IPOFinance - Cancer/inflammation-focused biopharma announces $14M private placementFinance - Cell-based company executive adopts Rule 10b5-1 prearranged stock sales planFinance - China-focused company revises guidance, issues preliminary Q3 resultsFinance - Clinical research organization reports second quarter financial resultsFinance - Commercial health benefits company announces pricing for tender offersFinance - Company announces closing of $60M private placement of common stockFinance - Company's stock delisted, per its demand, from Berlin-Bremen stock exchangeFinance - Cryosurgical technology company closes second-round investmentFinance - DCI parent reports Q2 sales of approximately $3,172,000Finance - DNA-focused company announces third quarter 2004 financial resultsFinance - Dental Select buys out stock of shareholderFinance - Device company closes $2.735M private placementFinance - Device firm reports second quarter EPS up 50% to $0.09Finance - Device maker to restate some historical financial statementsFinance - Diagnostics company reports loss of $0.12 per shareFinance - Drug development company raised third round of financingFinance - Drug discovery company announced private placementFinance - Emisphere agrees to new terms for note repaymentFinance - Female condom company reports Q4 2004 resultsFinance - Food safety company announces financial resultsFinance - Four teams awarded inaugural translational cancer research grantsFinance - Funding available to build behavioral health service systemFinance - Games for Health project receives major fundingFinance - Genetics-focused biopharmaceutical company reports Q3 2004 financial resultsFinance - Health Care REIT, Inc., announces gross investments of $584.9M for 2004Finance - Health care venture capital investments increase 23% in 2004, publisher reportsFinance - Health discount company announces stock transferFinance - Health management company pays to saveFinance - HearUSA reports 16% increase in December revenuesFinance - Hearing aid developer, manufacturer announces acceleration of option vestingFinance - Hospice care provider expands credit facility to $50 millionFinance - Hospital company announces expected fourth quarter earnings shortfallFinance - Imaging technology services provider reports third quarter 2004 resultsFinance - InSightec parent announces completion of self-tender offerFinance - Individual disability, group insurer files shelf registration statementFinance - Laboratory files shelf registration statementFinance - Medical device company announces record annual revenues, reports Q4 2004 resultsFinance - Medical device company closes $26 million in financingFinance - Medical device company closes Series B funding roundFinance - Medical imaging software company announces record revenue in third quarter 2004Finance - Michigan insurer offers grants for community health projectsFinance - Michigan insurer provides grant to improve men's healthFinance - Nanotech company named to Merrill Lynch indexFinance - Nevada Cancer Institute gets $25 million "challenge grant"Finance - Note exchange offer by hospital operator expiresFinance - Oncology-focused medical device company announces third quarter 2004 resultsFinance - Online medical services provider reports third quarter 2004 resultsFinance - Online secure medical services provider completes $20 million private placementFinance - Owner of senior living facilities signs venture agreement with JPMorgan FlemingFinance - Pharma announces pricing of $65M of 2.50% convertible subordinated debenturesFinance - Pharma company provides financial updateFinance - Pharmaceutical company announces results for fiscal 2005 first quarterFinance - Pharmaceutical firm announces $12.5M private placement financingFinance - Pharmaceutical firm closes $11.6M financingFinance - Pharmaceutical firm reports loss of $0.09 per shareFinance - Pharmaceutical firm reports loss of $2.06 per shareFinance - Pharmaceutical firm sells $283M of senior convertible notesFinance - Protein-focused biopharmaceutical company reports Q3 2004 financial resultsFinance - Protein-misfolding-focused company closes on $16M round of fundingFinance - Regional Pennsylvania hospital association releases year-end financial reportFinance - Science-based growth company completes private bridge loanFinance - Science-based pharmaceutical company reports third quarter 2004 financialsFinance - Secure healthcare information company begins trading under symbol SCUIFinance - Service provider to morbidly obese patients reports third quarter 2004 resultsFinance - South Broward Hospital District awards $50 million investment mandateFinance - Technology company closes on $4.0 million private placement financingFinance - Theranostics company closes private offeringFitness & Wellness - Inflatable wedge holds door open for those looking to get in shapeFitness & Wellness - Olympic gold medallist Kristine Lilly leads kids in action pilot programFitness and Wellness - British marathoner releases DVD and video on power walking off the poundsFitness and Wellness - Health club group predicts over 10 million Americans will join club in 2005Fitness and Wellness - Minnesota yoga instructor's 'YogaLift' program wins 'Best of Fitness' honorsFood Contamination - F-specific coliphages detected by PCR in fresh market-ready produceFood Safety - Emerging trends of foodborne illness surveillance and prevention analyzedFood Safety - Food safety company's germicidal product passes U.S. EPA Protocal testingFood Safety - Genome comparison of four Campylobacter strains yields genetic markersFood Safety - Listeria food poisoning cases rose in '03Food-Borne Disease - Lysozyme augments antimicrobial activity of chitosan filmsFoot-and-Mouth Disease - Method to detect foot-and-mouth virus antibodies developedGallstone Disease - Eating nuts is associated with lower risk of gallstones in menGastric Bypass Surgery - Teen twins undergo controversial gastric bypass surgeryGastric Cancer Diagnostics - LOH genotyping may be independent prognostic indicator in gastric carcinomaGastroenterology - Findings describe new data in gastroenterology researchGastroenterology - Interferon-alpha and antisense K-ras RNA suppress pancreatic cancer cell growthGastroenterology - Synergy between acid and pepsin affects posterior laryngeal tissuesGastroesophageal Reflux Disease - New method of measuring esophago-gastric junction competence developedGastrointestinal Stromal Tumor - Double-balloon enteroscopy aids in diagnosis of gastrointestinal stromal tumorGene Research - WDR25 gene is widely expressed in human tissuesGene Silencing - Retroviral driven transfer of short hairpin RNA analyzes gene functionGene Transfer - Jet injection and electroporation deliver plasmids to large musclesGene Transfer - Nucleotides targeting anti-apoptosis protein bind to erythroleukemia cellsGeneric Drugs - Company announces the first approval of Ciclopirox CreamGeneric Drugs - Company launches Halobetasol Cream 0.05% (Rx), and Ointment 0.05% (Rx)Generic Drugs - Pharma company receives approval for generic AccuprilGeneric Drugs - Research: Generics provide consumers more savings than price controlsGeneric Drugs - Spain to suspend reference-price system, support genericsGenetic Disorders - Dendritic cells made to express intereukin-12 prevent atopic disordersGenomics - New research in the area of genomics detailedGenomics - Varied recombination rates may bias gene mapping studiesGenomics and Genetics - ChIP assay used to identify glucocorticoid receptor target genesGenomics and Genetics - Effects of tetrodotoxin exposure on human glial cells clarifiedGenomics and Genetics - Gene expression in cochlea and kidney characterizedGenomics and Genetics - Growth arrest pathway genes also regulate metabolism and mitochondriaGenomics and Genetics - Novel statistical system improves study of gene coexpression dynamicsGenomics and Genetics - PCR use assessed in high surface-to-volume ratio SiO2 microstructuresGenomics and Genetics - Robust toolkit developed for functional profiling of yeast genomeGeriatrics - Aging-focused pharmaceutical company opens new research labs in North CarolinaGeriatrics - Data: Florida nursing home residents receive higher quality of care than in 2002Geriatrics - Psychosocial intervention aids patients with age-related macular degenerationGeriatrics - Rhode Island proposes nursing home reformGeriatrics - Study of diuretics in elderly people says the benefits outweigh the risksGestational Diabetes - Oxidative stress involved in pathogenesis of gestational diabetesGlioma - Diffusion-weighted imaging values highlight brain tumor invasionGlioma - IFNgamma's inhibitory effect on COX-2 expression relevant to glioma therapy?Global Health - International commission would coordinate global relief effortsGlobal Health - Science should be at center of decision making for developing nationsGonadotropins - Gonadotropin subunit structure studied, role of disulfide bridges revealedGraft-Versus-Tumor Effect - Graft-versus-tumor effect following ASCT generated against solid tumorsGrants - Nevada Cancer institute receives $25 million matching-funds grantGrants - Univ. of Oklahoma Health Center sees grant increasesGroup B Streptococcal Infection - Effects of intrapartum penicillin prophylaxis studied in infantsGynecologic Surgery - Women need less morphine after hysterectomies with new treatmentGynecology - Company reports 2005 Medicare payment value for cryoablation therapyGynecology - Doppler flow studies don't differentiate leiomyomas from leiomyosarcomasGynecology - SU5416 controls enzyme signals to block ovarian cancer angiogenesisGynecology - Transcriptional switches initiate estrogen-regulated endometrial growthHIV/AIDS Epidemiology - Surveillance needed to track epidemiology of HIV among Mexican migrants in USHIV/AIDS Healthcare - Education positively associated with awareness of HIV/AIDS-related servicesHIV/AIDS Healthcare - Point-of-care rapid HIV testing may improve entry into healthcareHIV/AIDS Prevention - Acceptability of HIV prevention strategies in central Tanzania exploredHIV/AIDS Prevention - Comprehensive response to HIV could prevent 10 million AIDS deaths in AfricaHIV/AIDS Prevention - German pharmaceutical company continues commitment to HIV/AIDS communityHIV/AIDS Prevention - Indian media to boost government efforts in combating AIDSHIV/AIDS Prevention - Misconceptions about medical advances may lead to risky sex practiceHIV/AIDS Prevention - Multifaceted intervention strategy associated with lower HIV rates
HIV/AIDS Prevention - One in five HIV-positive men knowingly put sexual partners at riskHIV/AIDS Prevention - Policy policies analyzed that affect HIV prevention in Mexican migrantsHIV/AIDS Prevention - U.S. NIH overlooked problems in Uganda AIDS study, whistleblower saysHIV/AIDS Research - Anti-termination by SIV Tat requires flexibility of nascent TAR structureHIV/AIDS Research - HIV-1 Vpr-mediated G(2) arrest requires Rad17 and Hus1HIV/AIDS Research - Reports add new data to HIV/AIDS researchHIV/AIDS Research - Researchers publish new studies and findings in the area of HIV/AIDSHIV/AIDS Risk - Scientists discover key genetic factor in susceptibility to HIV/AIDSHIV/AIDS Therapy - AIDS Drug Assistance Program of Utah selects prescription benefit serviceHIV/AIDS Therapy - Acute interstitial nephritis associated with protease inhibitor atazanavirHIV/AIDS Therapy - Clinical cutoffs for TYPE HIV-1 resistance test establishedHIV/AIDS Therapy - Deferring HAART initiation until CD4 cells drop below 200mm3 is detrimentalHIV/AIDS Therapy - NNRTI capravirine reduces HIV-1 viral load in phase 1 studyHIV/AIDS Therapy - New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicityHIV/AIDS Therapy - Reports advance knowledge in HIV/AIDS therapy researchHIV/AIDS Therapy - Researchers describe findings in HIV/AIDS therapy studiesHIV/AIDS-Associated Infection - Saquinavir & miconazole synergistic against C. albicans & C. neoformans HIV/AIDS-Coinfection - T. cruzi infection long silent course in immunosuppressed HIV patientsHIV/AIDS-Related Disease - Tumid lupus erythematosus uncovered following HAART-related immune restorationHIV/AIDS-Related Nutrition - Vitamins C and E protect against AZT-induced oxidative stressHaemophilus Influenzae - Study shows higher incidence of H. influenzae type b than previously knownHair Studies - Forkhead gene Foxe1 required for hair follicle morphogenesisHealth Education - Cancer support talk radio show now heard via Internet and satelliteHealth Education - U.S. young people's views of sexual terms undergo big changesHealth Promotion - Blue Shield of California pays members for healthy behaviorHealth Promotion - Cigna behavioral health doubles online coaching programHealth Promotion - Kids dental program named one of five national modelsHealth Promotion - Medicare will help beneficiaries quit smokingHealth Promotion - Minnesota partnership for smoking cessation offers QUITPLAN servicesHealth Promotion - National Parent Leadership month to be observed in FebruaryHealth Promotion - Online resource for expectant parents helps pregnant women to quit smokingHealth Promotion - Prevention organization comments on Medicare coverage of smoking cessationHealth Promotion - Programs support employee wellnessHealth Promotion - VoiceAmerica Network airs "The Gary Null Show"Health and Politics - Post-apartheid cultural politics of HIV/AIDS in South Africa analyzedHealthcare Access - Alaska clinics hope to improve patient satisfaction and cut no-showsHealthcare Access - Barriers to infectious disease care among lesbians identifiedHealthcare Access - Cherokee Nation to build Muskogee clinic in OklahomaHealthcare Access - Coalition reaches consensus on priorities for improving healthcare qualityHealthcare Access - Healthy Finds helps Americans make educated decisions about health careHealthcare Access - New burn center celebrated at biosciences conferenceHealthcare Access - PA Governor announces agreement on nursing home assessmentHealthcare Costs - Americans have variety of domestic options for savings on drugsHealthcare Costs - California health insurance premiums continue double-digit increasesHealthcare Costs - Regulators approve rate increase for Parkersburg, West Virginia, hospitalHealthcare Costs - Report shows Wisconsin school districts could save with health insurance planHealthcare Costs - West Virginia faces mental health care crisisHealthcare Coverage - AHIP launches unique online resource on health savings accountsHealthcare Coverage - Arkansas Governor discusses healthcareHealthcare Coverage - California leader calls for more taxes to protect schools, healthcareHealthcare Coverage - Drug store chain stops accepting Ohio state employee prescriptions under planHealthcare Coverage - Financial corporation enters agreement to provide health savings plansHealthcare Coverage - GI societies call for insurance coverage for colorectal cancer screeningHealthcare Coverage - Gevity announces 2005 workers' compensation programHealthcare Coverage - Humana adds Newport Beach hospital to its ChoiceCare NetworkHealthcare Coverage - Humana adds out-of-pocket cost data as a consumer-focused enhancementHealthcare Coverage - Insurance company announces new product for health care providersHealthcare Coverage - Lawmakers look to help needy children, adults receive healthcareHealthcare Coverage - New DirigoChoice enrollees tout state health plan in MaineHealthcare Coverage - Pharmacy group offers tips to boost pharmacy drug benefits lingoHealthcare Coverage - Program launched to help uninsured with sleep disordersHealthcare Coverage - Simply Secure healthcare savings program to launch first quarter 2005Healthcare Coverage - U.S. HHS issues final regulation on access to group health coverageHealthcare Coverage - Unions bargain away healthcare for same-sex partners in New York townHealthcare Coverage - World leaders vow to work together to help tsunami victimsHeart Disease Mortality - Depression tied to higher risk of heart disease deathHeart Disease Risk Factors - Adiponectin reduced in acromegaly and normalized by growth hormone correctionHeart Disease Risk Factors - Endothelial dysfunction in women with PCOS related to insulin resistanceHeart Failure - Nursing professor wins prize for arteriosclerosis , heart failure reportHeart Surgery - Study: Mortality risk doesn't differ between sexes after PCIHeart Surgery - Transesophageal echocardiography unreliable for cardiac output assessmentHeat Shock Proteins - Structure of small heat shock proteins changed in response to pHHeathcare Costs - Missouri sees $7.7 Million in mental health services savingsHelicobacter pylori - Helicobacter pylori may play role in conjunctival MALT lymphomaHematology - Novel assay enables simultaneous analysis of specific platelet antibodiesHematology - Novel ligand display technology transduces hematopoietic cellsHematology - PECAM-1 mediates platelet aggregation on irradiated endothelial cellsHematology - Prenatal gene therapy corrects hemophilia B in immunocompetent miceHematology - Proangiogenic protein protects multiple myeloma from apoptosisHematology - Tests detect occult hepatitis B in North American hemodialysis patientsHematopoiesis - Follistatin and follistatin-related gene have distinct hematopoietic functionsHematopoietic Malignancy - Blocking constitutive STAT5 activation may treat hematopoietic malignanciesHemoglobinuria - Clostridium septicum mutants used to diagnose hemoglobinuriaHepatitis B Therapy - Peg-IF monotherapy effective in over one-third of patientsHepatitis B Virus - Thymalfasin has the potential to treat patients with chronic hepatitis BHepatitis C Therapy - Company reports results from phase Ia/Ib studies of Actilon for hepatitis CHepatitis C Virus - A HCV IRES-mediated translation initiation model clarifies domain functionHepatitis C Virus - Ampligen clinical program initiated in HIV patients with or without HCVHepatitis C Virus - CD4+CD25+ regulatory T lymphocytes encourage hepatitis C virus persistenceHepatitis C Virus - Man infected with hepatitis C during test diesHepatitis C Virus - Positive results from study of oral protease inhibitor for hepatitis C reportedHepatitis C Virus - Testing for hepatitis C should be routine for persons at increased riskHepatitis C Virus - Vial from Cardinal Health pharmacy part of hepatitis probeHepatitis Therapy - DHEA reduces hepatic inflammation in hepatitis modelsHepatoblastoma - Single-agent cyclophosphamide ineffectual in refractory, relapsing HB patientsHepatocellular Carcinoma - Risk of delirium after liver resection for hepatocellular carcinoma studiedHepatocytes - Some gene activities in hepatocytes do not require growth factor receptorHereditary Antithrombin Deficiency - Company provides ATryn program updateHerpes Risk Factors - Study finds herpes virus in 98% of healthy participantsHerpes Simplex Virus - Herpes simplex virus studied, activity of alpha-helical peptides revealedHormone Replacement Therapy - Adding methyltestosterone to esterified estrogen improves lipoprotein profileHormone Replacement Therapy - Overall risk of developing hypertension during HRT is lowHormone Replacement Therapy - Review supports link between HRT and strokeHuman Genome - Laboratory devises technique to explain patterns of gene regulationHuman Papillomavirus - CDK inhibitor inhibits HPV-16 E7-induced numerical centrosome anomaliesHuman T Cell Leukemia Virus - HTLV-1 Tax ubiquitination modulates its activityHuman T-Cell Leukemia Virus - Stable ubiquitination of HTLV-1 tax required for proteasome bindingHyperglycemia - VEGF and high glucose levels mediate placenta growth factor activityHypertension - Calcium channel blockers boost women's risk of CVD death than other treatmentsHypertension - DETA/NO has potent blood pressure lowering effectsHypertension - Gene mapping supports a relationship between the Add1 gene and blood pressureHypertension - Genes don't explain higher blood pressures among African AmericansHypertension - New findings in the area of hypertension describedHypertension - New findings in the area of hypertension detailedHypertension - Sodium intake influences vasoconstriction in cold-induced hypertensive ratsHypertension - TDI analysis could detect precocious LV global diastolic dysfunctionHypertension - Transfer function to calculate aortic from upper limb pressure validatedHypodermoclysis - Vitrase launches in the United StatesHypogonadism - Companies announce approval of Tostrex gel in first European countryHypothyroidism - Adjusting pre-conception L-T4 dose may yield adequate maternal thyroid functionImaging - Gonad capsule effective method for blocking radiation to testes from scanImaging - Knowledge of ECG artifacts during high-field MRI is essentialImaging - LV strain is not uniformly distributed over the wallImaging - MRI deconstructs brain's complex networkImaging - MRI technique is integrated for deformation field reconstructionImaging - Method accurately segments vessels from MRA dataImaging - Study determines commonly used contrast agent safe for "universal use" in CTImaging - Technique provides detailed tomographic images of the inner organsImmunology - Active subgroup of small intestinal intraepithelial lymphocytes identifiedImmunology - Beta-casein (1-28) exerts mitogenic effect on T and B lymphocytesImmunology - Drm/Gremlin and Dan interact with Slits and inhibit monocyte chemotaxisImmunology - Researchers provide details of new studies and findings in the area of immunologyImmunology - Researchers report details of new studies and findings in the area of immunologyImmunology - Studies add new findings to immunology body of knowledgeImmunology - Studies advance knowledge in immunology researchImmunosuppression - Leflunomide protects the liver from T-cell-mediated injuryInfant Mortality - Cuba says its infant mortality rate for 2004 was lowest in Latin AmericaInfection - Inhibition of human and Leishmania donovani topoisomerases revealedInfections - Growth of Escherichia coli O157:H7 inhibited in vitro by colicinInfectious Disease - Poly(ADP-ribose) polymerase-1 inhibition disrupts the chlamydial life cycleInflammatory Bowel Disease - Coinfection with CMV frequent in IBD patients on immunosuppressive therapyInfluenza - Flu activity picking up in Colorado; vaccine restrictions liftedInfluenza Vaccine - Alabama health officials expand list of people who can get flu shotsInfluenza Vaccine - Flu vaccine to be more widely available in New MexicoInfluenza Vaccine - Missouri relaxes guidelines for flu vaccineInfluenza Vaccine - More adult flu vaccine available in FloridaInfluenza Vaccine - New Jersey eases restrictions on influenza vaccineInfluenza Vaccine - New York relaxes flu shot restrictionsInformation Technology - American TeleCare selected to participate in VA's telehealth programInformation Technology - Cameras and computers enable U.S. doctors to watch over patients from afarInformation Technology - Caritas Christi Health Care's network deploys security platformInformation Technology - Clinical information software provider announces go-live at Mississippi hospitalInformation Technology - Company awards $4.6 million for studies of cardiac safety monitoring servicesInformation Technology - Company launches consultancy to provide healthcare-related wireless serviceInformation Technology - Electronic medical records company ranked lead provider by IT advisory serviceInformation Technology - Florida insurer upgrades online resource for uninsured FloridiansInformation Technology - Georgia Chiropractic Association chooses payment processing systemInformation Technology - Health information company launches enhanced health news channelInformation Technology - InFORM Radiology Information System to add billing functionInformation Technology - Internet-based company launches life sciences information channelInformation Technology - Medical web site to provide health-related content on Earthlink start pageInformation Technology - Pharma firm adopts MDL Isentris platform to boost R&DInformation Technology - Rhode Island hospital implements emergency department information systemInformation Technology - Software company launches new practice management systemInformation Technology - Software delivers real-time electronic device history record solutionInformation Technology - Technology company launches data collection softwareInformation Technology - Technology company to install IT infrastructure for Wockhardt PharmaceuticalsInformation Technology - University health system selects communications protection software suiteInformation Technology - Updated commerce-optimization software releasedInformation Technology - Voluntary health organizations, publishers announce information initiativeInformation Technology - Wireless healthcare making money for technology companies, report analyst saysInjury Prevention - Children at risk from unexploded military materialInjury Prevention - Injury toll in U.S. homes tops 12 million yearlyInjury Prevention - Most alcohol-related plane crashes occur at night, in bad weatherInjury Prevention - Parents more likely to follow advice if they trust their children's doctorsInjury Prevention - Snowy roads lead to more crashesInsemination - Apis mellifera insemination can produce different sperm survivalInterstitial Cystitis - IC is more prevalent in managed care population than previously thoughtIrritable Bowel Syndrome - Study of pro-motility agent shows improved work productivity in women with IBSIschemia - Neuroprotection analyzed, role of fructose-1,6-bisphosphate revealedIschemia - Reports describe recent advances in ischemia researchIschemia - Researchers' findings advance ischemia researchIschemia/Reperfusion - Studies describe new findings in ischemia/reperfusion researchKaposi Sarcoma-Associated Herpes Virus - Small GTPase Rac1 links KSHV vGPCR to cytokine secretion and paracrine neoplasiaKaposi Sarcoma-Associated Herpesvirus - Fetal mesencyhmal stem cells susceptible to KSHV infectionKaposi Sarcoma-Associated Herpesvirus - Findings describe new data in kaposi sarcoma-associated herpesvirus researchKearns-Sayre Syndrome - Deleted mitochondrial DNAs reduced by ketogenic treatmentKidney Disease - Altered podocyte-derived VEGF assembly may precipitate diabetic glomerulopathyKidney Infection - Sexual behavior, genetic factors increase risk in women under 50Knee Replacement - Factors determining wear in Press-Fit Condylar modular system identifiedKnee Replacement - Mini-midvastus approach improves TKA outcomeKnee Replacement - Risks of bilateral total knee replacement elucidatedKnee Replacement - Two-stage reimplantation of infected TKA has high long-term success rateLab Technology - Brand perceptions of scientific instrumentation suppliers establishedLactation - Breast milk samples from different donors contain similar oligonucleotidesLanguage - Spanish whistles get brain's language center tickingLead Poisoning - Low levels of lead affect proliferation and differentiation of embryonic NSCsLegal Issues - Augsburg flu shot case referred to federal prosecutorsLegal Issues - Hypnotist reaches plea deal over charges of sex with patientsLegal Issues - Indiana seeks probation for nursing homeLegal Issues - Jury finds for Utah women in diet drug fen-phen verdict with $2.1 million awardLegal Issues - Lilly denies report of missing Prozac documentsLegal Issues - New health law sometimes poses problem for policeLegal Issues - Newspaper reviews human services system privatizationLegal Issues - Payments settle allegations over free vaccinesLegal Issues - Pfizer sued over painkillerLegal Issues - Settlement reached in brain harvesting lawsuitLegal Issues - South Carolina hospitals join to fight lawsuitsLegal Issues - Special prosecutor appointed in brain harvest probeLegal Issues - U.S. Attorney reports guilty plea in kick-back caseLegal Issues - U.S. court upholds patent infringement suit against generic antibiotic makerLegionella pneumophila - Legionella pneumophila genomes have high plasticityLeishmania Diagnostics - Real-time RT-PCR and PCR-ELISA quantifies L. infantum from tissue biopsiesLeishmaniasis - Drug company receives regulatory approval in Germany for leishmaniasis therapyLeishmaniasis - New findings in the area of leishmaniasis describedLeptin Studies - Leptin levels are dependent on sleep durationLesch-Nyhan Disease - Novel mutations involved in HPRT deficiency identifiedLeukemia - Chemotherapy drug combination shows promise for leukemia treatmentLeukemia - Girl in remission after leukemia diagnosis, twin sister's organ donationLeukemia - Higher BMI associated with increased risk of AML, but not CLL in older womenLeukemia - Isolated extramedullary relapse appears common after Chemo-DLILeukemia - Oral valacyclovir may protect against herpes during high-dose chemotherapyLipid Studies - Novel FA2H gene encodes a fatty acid 2-hydroxylaseLipoprotein - Lipoprotein related enzymes studied, role of high density lipoprotein revealedLiposomal Delivery - Production of TGF-beta studied, role of a kinase and liposomes revealedListeria - Epidemic L. monocytogenes dairy farm strain causes sporadic human illnessLiver Cancer - Genes with prognostic value in hepatocellular carcinoma identifiedLiver Cancer - Quercetin induces selective growth inhibition/apoptosis in hepatic tumor cellsLiver Cirrhosis - Neuropsychiatric test developed for subclinical hepatic encephalopathyLiver Disease - Action plan released addressing burden of liver diseaseLiver Disease - CYP2E1 inhibitors oppose liver injuryLiver Disease - NIH action plan charts future challenges for researchLiver Disease - Nuclear import of proinflammatory transcription factor fuels liver cell deathLiver Fibrosis - A dual reporter gene transgenic mouse aids hepatic fibrogenic investigationLiver Fibrosis - Antioxidant boosters staunch fibrosis in rodent liversLow Back Pain - Tool identifies low back pain patients who will benefit from spinal manipulationLung Cancer - PI3-kinase pathway involved in early progressionLung Research - Technique allows lung-specific delivery of reagentsLung Transplant - Living-related lobar lung transplants may increase donor availabilityLysosomal Storage Disease - Alpha-N-acetylglucosaminidase replacement treats Sanfilippo syndrome modelsLysozyme - Lysozyme activity analyzed, effects of Ni2+ revealedLysteria monocytogenes - L. monocytogenes attachment to alfalfa sprouts leads to irrigation changesMachado-Joseph Disease - Cell death plays a role in the pathogenesis of Machado-Joseph diseaseMacular Degeneration - Study shows drug effectively treats neovascular age-related macular degenerationMalaria - Travelers to Dominican Republic should take prophylaxisMale Infertility - Sperm-sorting machine electronically filters healthy sperm for IVFMalignant Mesothelioma - MM cells expressing Slug have increased resistance to chemotherapeutic agentsMarket Analysis - What is driving the rise in over-the-counter drugs?Mastitis - Calcium inhibits bap-dependent multicellular behavior in Staphylococcus Medical Device - Opsonization of wear particles regulates macrophage responsesMedical Device - Robotic pyeloplasty reviewedMedical Device Reimbursement - ExacTrac X-Ray 6D technology now eligible for reimbursementMedical Devices - Capture detection in cardiac pacing reviewedMedical Devices - Counterpulsation algorithm devised for moving-actuator type pulsatile LVADMedical Devices - Dynamic characteristics of VentrAssist implantable rotary blood pump determinedMedical Devices - Highly integrated sphincter prosthesis developedMedical Devices - Internet-based home care monitoring system developedMedical Devices - Medical device company gets IDE for embolic protection filters in clinical trialMedical Devices - Optimum placement of ports in robotic urinary tract surgery outlinedMedical Devices - Valve-specific parameters for mechanical heart valve cavitation determinedMedical Errors - Deadly drug mistakes spike at the start of each monthMedical Errors - New medication management products, consulting services launchedMedical Errors - Robot mixes medications, prepares syringesMedical Errors - Surgeon who left patient on operating table to pay $1.25 million settlementMedical Imaging - First magnetic resonance imaging applications lab to be built in Oxford, U.K.Medical Imaging - Flat detectors increasingly replacing x-ray film, company reportsMedical Imaging - IT company awarded 3-year medical center contract for digital imaging servicesMedical Imaging - Ultrasound systems company introduces zone sonography ultrasound platformMedical Malpractice - Group of doctors says medical reform bill should become lawMedical Malpractice - U.S. President pushes for lawsuit limits in county dubbed 'judicial hellhole'Medicare - Company's managed care coverage for Medicare beneficiaries expanded by U.S. CMSMelanoma - Order of treatment critical for avoiding toxicityMeningiomas - Galectin-3-binding sites, S100B may affect atypical meningioma aggressivenessMenopause - Anti-mullerian hormone is promising predictor of menopausal transition.Mental Health - Effects of lithium on neuronal growth cone behavior determinedMental Health - Effects of oral hormone receptor antagonist studied in a primate stress paradigmMental Health - Hundreds of disaster survivors seek counselingMental Health - Money issues leading cause of holiday stress for AmericansMental Health - New treatment for depression approved in EuropeMental Health - Quetiapine elevates noradrenaline and dopamine release in rat prefrontal cortexMental Health - Rgs2 is a quantitative trait gene for anxiety in miceMergers & Acquisitions - A4 Health Systems acquires Canopy SystemsMergers & Acquisitions - AXIA Health Management launched, merges with HealthCare DimensionsMergers & Acquisitions - American Red Cross Transplantation Services tissue banking assets to be acquiredMergers & Acquisitions - Biotech company puts merger plans with Panacos Pharmaceuticals on holdMergers & Acquisitions - California company acquires BestCareMergers & Acquisitions - Company acquires four dialysis facilitiesMergers & Acquisitions - DTLL, Inc., closes on acquisitionMergers & Acquisitions - Definitive agreement to sell optical retail chain announcedMergers & Acquisitions - Developers of Health Data Focus mergeMergers & Acquisitions - Dragon extends share purchase agreement in connection with proposed acquisitionMergers & Acquisitions - Ecolab acquires water-care companyMergers & Acquisitions - Embryo Development Corp. discusses potential mergerMergers & Acquisitions - Eye Care International acquires N-CAMMergers & Acquisitions - French contract research organization acquiredMergers & Acquisitions - Health curriculum provider acquired by healthcare marketing firmMergers & Acquisitions - HealthCare Partners merges with Harriman Jones Medical GroupMergers & Acquisitions - IMV Ltd. acquires AuntMinnie.com businessMergers & Acquisitions - Independence Holding Company acquires Health Plan Administrators, Inc.Mergers & Acquisitions - Institutional pharmacy provider acquires UniScripts, Inc.Mergers & Acquisitions - Letter of intent issued to acquire Synova HealthcareMergers & Acquisitions - Medical device maker enters into agreement to acquire stent developerMergers & Acquisitions - Medical hand-held device company postpones acquisition of Israeli companyMergers & Acquisitions - Medical transcription technology company acquires Avicis, formerly HealthScribeMergers & Acquisitions - Momentum Computer, Inc., acquired by computer companyMergers & Acquisitions - Nanotechnology company merges with C SixtyMergers & Acquisitions - Oral care product development business acquired for EUR 8MMergers & Acquisitions - Pharma company to acquire ProBio InternationalMergers & Acquisitions - Pharmaceutical company merger approvedMergers & Acquisitions - Therapeutics company acquires interest in Alzheimer-focused EllipsisMergers and Acquisitions - Medical closure system company to sell drug delivery businessMetabolic Syndrome - Growth hormone and placental lactogen genes linked to metabolic syndromeMetabolic Syndrome - Hepatic lipase mRNA, protein, and enzymes increased in insulin resistanceMetabolic Syndrome - Research shows metabolic syndrome drug market to increase by 2013Metabolic Syndrome - Studies add new findings to metabolic syndrome body of knowledgeMetabolic Syndrome - Weight, fitness and lifestyle important contributors to metabolic syndromeMetabolic Syndrome - von Willebrand factor does not predict development of metabolic syndromeMetabolism - Energy expenditure in elderly investigatedMetalloproteins - Alpha-helical coiled coil peptide that binds Ni(II) and Cu(II) designedMetastases - Scientists study how cancer cells get out of controlMetastatic Melanoma - Taxanes may be treatment option for metastatic melanomaMicrobiology - Involvement of linear plasmids in aerobic biodegradation of vinyl chlorideMigraine - Handout focuses on menstrual migraineMigraine Therapy - Cost of prophylactic migraine treatments outlinedMitrochondria - Mitochondrial oxoglutarate carrier studied, solution structure clarifiedMolecular Biology - Protein transformation gives new twist to medical researchMolecular Biology - Research-products provider introduces pre-poured Agar plates for bacteria growthMolecular Biology - Researchers report on carbohydrate-carbohydrate interactions in cell recognitionMolecular Biology - tRNA global structure varies more than had been supposedMolecular Diagnostics - Multiplexed RT-PCR valuable for high throughput screening applicationsMonoclonal Antibody - Analysis of myeloma cell lines for antibody production conductedMonoclonal Antibody - System to select cells producing glycosylated single-chain Fv developedMovement - Exploring the brain's internal stopwatchMucosal Immunization - Research add new data to mucosal immunization body of knowledgeMultiple Myeloma - Cancer drug study results indicate potential for treating multiple myelomaMultiple Sclerosis - Alpha lipoic acid has implications as a therapy for multiple sclerosisMultiple Sclerosis - Software selected to support multiple sclerosis research partnershipMutagenesis - Electrochemiluminescence assay shows point mutations in cancer samplesMutagenesis - Researchers' data advance mutagenesis researchMutagenesis - Topoisomerase inhibitors pursue chromatin to alter paternal chromosomesMyelodysplastic Syndrome - MoDCs in MDS have abnormalities that contribute to defective immune responseMyocardia - PPARalpha may mediate mitochondrial response to thyroid hormoneMyocardial Infarction - AB5000 ventricle patient supported for more than 37 daysMyocardial Infarction - Cord blood cells limit heart attack damage in animal studyMyocardial Infarction - Normal LV wall motion does not exclude myocardial infarctionMyocardial Infarction - RV involvement in MI should be detected as early as possibleMyocardial Infarction - Working while ill boosts heart-attack riskMyopathy - Gene mutations associated with congenital myopathies produce varying effectsNanoparticles - Biomolecular interaction between biotin and streptavidin detectedNanotechnology - Nanotechnology company introduces new product lineNanotechnology - New protein holds promise for use in medicine and nanoscienceNanotechnology - Research shows nanomaterials are establishing commercial presence in U.S.Natural Medicine - Phyllanthus amarus extract reduces HIV replicationNeoplasia - Bcl-2-related genes important in tumor initiation/progression/therapy responseNeovascularization - Ex vivo murine aorta cultures model angiogenesisNeovascularization - Mast cell-derived angiopoietin-1 promotes plasmacytoma growthNeurodegeneration - Beta-synuclein gene transfer protects mice from nervous system degenerationNeurodegeneration - Geranylgeranylation inhibition mediates HMG-CoA reductase inhibitorsNeurodegeneration - New findings in neurodegeneration describedNeurodegenerative Disease - Cell-specific patterns of tau-dependent process formation identifiedNeurodegenerative Disease - Protein stability unaffected by polyglutamine expansion in ataxin-3Neurofibromatosis - Brain tumor study reveals why treatment efforts fail in genetic disorderNeurology - Genetic and epigenetic events highlight the etiology of autismNeurology - Inositol monophosphatase 2 expression is implicated in bipolar disorderNeuroscience - Coding and decoding of spatial position by nervous system elucidatedNeuroscience - Effects of PVN spider venom on blood-brain barrier permeability clarifiedNeuroscience - Effects of fluoxetine on locus coeruleus in early protein deprivation assessedNeuroscience - Effects of microtubule-stabilizing agent Taxol in rat hippocampus characterizedNeuroscience - Estradiol uses a receptor-dependent mechanism to protect hippocampal neuronsNeuroscience - Hepatic glucose responses to electro-acupuncture characterized in ratsNeuroscience - Hepatocyte growth factor revitalizes memory function after cerebral ischemiaNeuroscience - Human alpha-synuclein impairs neurogenesis in miceNeuroscience - Increasing attention has provided information about social phobiaNeuroscience - Ligation preconditioning protects the rodent brain from hypoxia-induced injuryNeuroscience - Mab35 immunoreactivity characterized in rat magnocellular neuronsNeuroscience - New findings in the area of neuroscience detailedNeuroscience - New research in the area of neuroscience detailedNeuroscience - Novel ALS2-derived somatodendritic marker for neurons identifiedNeuroscience - Novel assay ATP release in molluscan central nervous systemNeuroscience - Online microdialysis-CE system used to monitor rat D-serine dynamicsNeuroscience - Recent findings in neuroscience describedNeuroscience - Recent findings in neuroscience provide new insightsNeuroscience - Representation of sound intensity in rat auditory cortex characterizedNeuroscience - Researchers detail new studies and findings in the area of neuroscienceNeuroscience - The Wilms tumor gene is overexpressed in primary astrocytic tumorsNeuroscience - Vitronectin regulates I h current in mouse hippocampal neuronsNeutropenic Sepsis - Infusion of G-CSF may reduce duration, severity of neutropeniaNitric Oxide - Endogenous NO modulates aldosterone synthesis in humansNitric Oxide - NO synthesis inhibition affects physiological response to mental stressNitric Oxide - Review explores the causes of nitric oxide insufficiencyNon-Hodgkin Lymphoma - Pesticide exposure may be associated with increased risk of NHL among womenNon-Small Cell Lung Cancer - Cancer vaccine trial data updatedNosocomial Infections - Isolation of ICU patients with MRSA does not prevent cross-infectionNutrition - Dynamic rheology of gelatine-sugar composites measured during agingNutrition - Infant formula quality studied, role of specific saccharide ratio revealedNutritional Supplements - Alliance calls for donation of children's vitamins for Asian tsumani victimsObesity - Frequent fast food meals increase weight, diabetes riskObesity - Insufficient sleep associated with overweight and obesityObesity - Maker of handheld mobile devices introduces applications for weight managementObesity Genomics and Genetics - Mutation in PPAR-gamma promoter linked to partial lipodystrophyObesity Pathogenesis - Adiponectin linked to increased weight gain in small infantsObesity Pathogenesis - Brain region-specific forms of obesity linked to agouti expressionObesity Pathogenesis - IL-6 regulates adipose tissue lipid metabolism and leptin productionObesity Pathogenesis - New data illuminates research in obesity pathogenesisObesity Risk Factors - Decisional balance measures for adolescent sedentary behavior developedObesity Surgery - Gastric bypass successful in obese patient with myasthenia gravisObesity Surgery - Gastric outlet obstruction caused by total band erosionObesity Surgery - Silicone tube of gastric band causes small bowelObesity Surgery - Studies advance knowledge in obesity surgery researchObesity Therapy - Findings advance knowledge in obesity therapy researchObesity and Diabetes - Age has independent effect on insulin sensitivity and beta-cell functionObesity and Diabetes - Beta-cell function and insulin sensitivity associated with body fatnessObesity and Diabetes - Ciliary neurotrophic factor decreases weight and improves metabolismObesity and Diabetes - Free fatty acid levels modulate microvascular functionObesity and Diabetes - Intranasal insulin reduces body fat in men but not in womenObesity and Diabetes - Mitochondrial remodeling in adipose tissue associated with obesityObesity and Diabetes - Phosphatidylinositol/AKT/atypical PKC pathway improves insulin sensitivityObesity and Diabetes - c-Cb-deficient mice have reduced adiposity and improved insulin actionObstetric Anesthesia - General anesthesia used in about 20% of cesarean sections in Singapore hospitalObstetric Anesthesia - U.S. medical center conducts retrospective analysis of anesthesia failuresObstetric Nursing - "Kangaroo care" treats young woman's grief, anxiety, perinatal problemsObstetrics - Birth simulator helps identify least forceful way to manage problem deliveriesObstetrics - Cerebral hemodynamic changes present in women who develop preeclampsiaObstetrics - Conditional month difference, imputed month midpoint better for timing eventsObstetrics - Higher dose of clomiphene doesn't appear to increase risk of poor outcomeObstetrics - Intrauterine inflammation increases with prolonged latency after PPROMObstetrics - Nearly half of extremely premature babies have significant disabilities laterObstetrics - New findings in obstetrics describedObstetrics - Newer antidepressants don't appear to adversely effect pregnancy outcomeObstetrics - Researchers' findings advance obstetrics researchObstetrics - University Hospitals examines screening of babies for drugsOccupational Health - Welding fumes suppress lung defense responses after bacterial infectionOlfaction - Dopaminergic phenotype analyzed, olfactory differentiation revealedOncogenesis - Hepatitis C virus transfection produces liver cell growth and tumorigenesisOncogenesis - Research in oncogenesis provides new insightsOncology - Chromosome changes are prognostic indicators in multiple myeloma patientsOncology - Integrin signals link survival elements in recurrent prostate cancerOncology - Interleukin-10 may enable liver cancer to evade immune response mechanismsOncology - Paclitaxel halts angiogenesis at similar rates despite dissimilar schedulingOncology - Putative HOX11 target genes identifiedOncology - Researchers provide details of new studies and findings in the area of oncologyOncology - SPRY2 activity in presence of wild-type and mutant BRAF clarifiedOncology - Studies advance knowledge in oncology researchOncology - T cell type cancer predominates in Korean primary hepatic lymphoma casesOncology - Thrombin is involved in tumor invasionOncology - Ultrasonography accurately detects lymph-node invasionOphthalmology - Educating employees about eye safety can protect their visionOral Cancer - Dietary zinc affects cox-2 expression and esophageal and tongue carcinogenesisOral Cancer - Finding abnormal p16 methylation pattern may aid in early oral cancer detectionOral Health - Midland, Texas, child youngest ever to have wisdom teeth pulledOrthopedics - Bone specialists develop high-tech answer to patient careOrthopedics - Tool to examine bone quality for space, earth-based diagnosisOsteoporosis - Bone response to PTH and high-dose E2 involves patterned gene regulationOsteoporosis - Effects of alendronate last longer after discontinuation than estrogenOsteoporosis - Findings advance knowledge in osteoporosis researchOsteoporosis - Hip fracture estimated to comprise 0.1% of global burden of disease in 1990Osteoporosis - Research add new data to osteoporosis body of knowledgeOsteoporosis - Researchers' findings advance osteoporosis researchOsteoporosis - Studies add new findings to osteoporosis body of knowledgeOsteoporosis - Studies describe new findings in osteoporosis researchOsteoporosis - Wyeth selects drug targets in osteoporosis collaboration with Belgium companyOtorhinolaryngology - Across- and within-channel envelope interactions characterizedOtorhinolaryngology - Clinical features of temporal arteritis reviewedOtorhinolaryngology - Cochlear implant magnet migration reportedOtorhinolaryngology - Functional effects of esophageal caustic strictures determined in childrenOvarian Cancer - Assay combination has potential to double response rate to chemotherapyOvarian Cancer - Cell lines analyzed using array-based comparative genomic hybridizationOvarian Cancer - Company enrolls, initiates reviews phases of clinical trials for cancer drugOvarian Cancer - Progesterone signaling appears to influence disease riskPain Medicine - Novel encapsulation method improves efficacy of intrathecal chromaffin cellsPain Medicine - Outcomes of anesthetic-delivery device following mastectomy reportedPancreatic Surgery - Management of inflammatory arrosion hemorrhage describedParkinson Disease - Parkinson disease affects well being of patients' adolescent and adult childrenPatents - Anesthetic delivery system developer announces new patent protectionPatents - Biotech company acquires gene encoding patent from Akademikliniken AB of SwedenPatents - Company gets patent for differentiating hESCs into neural cellsPatents - Company secures license to SirT2 and SirT3 patents from University of CaliforniaPatents - Diagnostics products developer announces patent issuancePatents - European patent granted for learning and memory compoundPatents - Medical device maker acquires intellectual property portfolioPatents - Patent approved in Canada for bone graft materialPatents - Patent granted for detecting environmentally toxic dioxin-like chemicalsPatents - Patent infringement lawsuit filed against Insmed for growth hormone treatmentPatents - Remote ICU monitoring technology company challenges Visicu's patent rightsPatents - Surgical technology company announces patent for bladeless tip technologyPatents - Telemedicine patent granted in AustraliaPatents - U.S. patent allowed for stabilized hydroxyvitamin D2 productsPatient Care - Nonprofit group takes photos of ailing kidsPatient Compliance - Compliance is compromised when patients are treated with multiple pillsPatient Safety - AIG Healthcare joins forces with patient groupPatient Safety - Forum for chief nursing officers emphasizes role of nurses in patient safetyPatient Safety - Quality measurement tools used for adult hospitals can apply to children'sPediatric Cardiology - Nine-month-old girl receives nonsurgical heart valve replacementPediatric Oncology - Auto company retailers help raise $1 million for pediatric cancer researchPediatrics - Incidence of surgeries in children with childhood orthopedic diagnoses studiedPediatrics - Narrow measures govern neurogenetic models of ADHD etiologyPediatrics - New clinical guidelines advise when to treat flat feet in childrenPediatrics - Obesity rising among U.S. preschoolersPediatrics - Vision system effective in detecting preverbal children's vision deficitsPeptide Signaling - Chemotaxis triggering studied, synergistic effect of two regulators revealedPerception - How does the brain tune out odors?Perception - Scents and emotions linked by learningPeripheral Blood - Recombinant IL-2 analog induces proliferation of unstimulated T cellsPersonnel - Agriculture processing company announces retirement of presidentPersonnel - Allergy-focused company appoints Deborah A. Smeltzer as CFOPersonnel - Arkansas leader appointed to U.S. House committee covering energy health issuesPersonnel - Biopharma company announces vice president, general counsel and secretaryPersonnel - Biopharma company names CEOPersonnel - Biopharma company names new board memberPersonnel - Biopharmaceutical company names director of pharmaceutical developmentPersonnel - Biotech company announces promotions, appointmentsPersonnel - Biotech company names Thomas E. Shenk to board of directorsPersonnel - Biotechnology company appoints director of regulatory affairsPersonnel - Biotechnology company names vice president, worldwide salesPersonnel - Brain monitoring technology firm names David W. Feigal Jr. to boardPersonnel - Byproducts company announces board addition, president and CEOPersonnel - California controller names Philip Pizzo, MD, to stem-cell oversight committeePersonnel - Cardiologist elected Society for Women's Health Research board chairPersonnel - Charles B. O'Keeffe named to board of Florida-based pharmaceutical companyPersonnel - Charles Craig named president of BIO's Georgia affiliatePersonnel - Children's Hospital of Pittsburgh names new president and CEOPersonnel - Dental services company announces reorganizationPersonnel - Digital surgical device company names Robin Blackstone, MD, to boardPersonnel - Dow AgroSciences executive joins Indiana life sciences initiativePersonnel - Dr. Goran Ando joins board of directorsPersonnel - Drug development company names science and technology advisorsPersonnel - Eclipsys names John A. Adams as executive VP and chief administrative officerPersonnel - Former Massachusetts governor Jane Swift appointed to health insurer's boardPersonnel - Glen Tullman, CEO, named to leadership council of clinical software providerPersonnel - Health minister, battling cancer, says he likely will resignPersonnel - Health performance measurement company announces addition to boardPersonnel - Healthcare marketing research consultancy announces appointments in EuropePersonnel - Hythiam names vice president of scientific affairsPersonnel - Lab chip maker names Thomas T. Higgins chief financial officerPersonnel - Leslie J. Williams named president, CEO of pharmaceuticals companyPersonnel - Maclyn McCarty, MD, genetic research pioneer, dies at 93Personnel - Medical device company announces board member additionPersonnel - Medical device company announces new board membersPersonnel - Medical device company appoints member to boardPersonnel - Medical device firm announces management expansionPersonnel - Medical technology company appoints vice president of business developmentPersonnel - New York City hospitals chief leaving post for private-sector jobPersonnel - Pain-management company announces executive appointmentsPersonnel - Pharmaceutical firm appoints Robert Roe to board of directorsPersonnel - Plant technology company appoints director of finance and administrationPersonnel - Prescription savings company names Mark Chamness VP of pharmacy networksPersonnel - President names former Virginia Secretary of Health domestic policy adviserPersonnel - Richard C. Williams named interim CEO of specialty biopharmaceutical companyPersonnel - Therapeutics company names member to boardPersonnel - Vijay Sondhi appointed chief financial officer by pharmaceutical companyPersonnel - West Virginia leader signals departure from Health agencyPersonnel - William Nuerge named CEO of women's health and urology focused drug companyPersonnel - William Siart resigns from board of dental-products companyPersonnel - Wyoming leader plans to step down as health directorPersonnel - Wyoming leader to chair Senate health committeePheromones - Enhancement of pheromone response in yeast reportedPhilanthropy - Antibiotics valued at $50M donated to AmeriCaresPhilanthropy - Florida philanthropist Alexander W. Dreyfoos gives Scripps Institute $1 millionPhilanthropy - GPI to help bring medical aid to South AsiaPhilanthropy - ING Vysya Foundation, Sev Mandir to support water harvesting project in IndiaPhilanthropy - Pharmaceutical company contributes $300K, products to tsunami relief effortsPhilanthropy - Records show $1 billion donated to faith-based groupsPhosphatase - Expression, characterization, and analysis of purple acid phosphatase reportedPhysiology - Caveolin-1 analyzed, functional form necessary for alpha-hemolysin assemblyPhysiology - Increased uterine flow impedance found in older pregnant womenPhysiology - Organ of corti potentials and the motion of the basilar membrane revealedPhysiology - Potassium channel subunit and aquaporin-4 are localized to cerebellar pinceauPhysiology - Study evaluated effects of nutritional stress on AMPK activity in vivoPhysiology - Study examined fatty acyl CoA synthetase from Antarctic fishesPlague - Virulence factor expression in Yersinia pestis characterizedPlant-based Medicine - Tea tree oil's antimicrobial activity studied in Staph. aureus-infected woundsPlatelets - rFVIIa results in activation of FIX to form additional tenase complexesPneumococcal Vaccines - Recent findings in pneumococcal vaccines describedPneumonia - Procalcitonin a prognostic marker for outcome in pneumoniaPompe Disease - Company files for European approval of Myozyme for Pompe diseasePorphyromonas Gingivalis - Oxidative damage repair studied in Porphyromonas gingivalis Positron Emission Tomography - Application demonstrated new radiotracer to be safe and usefulPre-eclampsia - Researchers find protein predicts pregnancy complicationPreeclampsia - Protein in urine may warn of preeclampsia riskPremature Birth - Outlook is bleak for the smallest premature babies: 80% have impairmentPreventive Medicine - 20M smokers resolve to quit in 2005 againPreventive Medicine - Medical Reserves Corps offers Heart Healthy Firefighter programProduct Licensing - Biopharmaceutical company licenses human protein BPI to Zephyr Sciences, Inc.Product Licensing - CAD, 3-D imaging companies announce licensing agreement for computed tomographyProduct Licensing - CTI licenses Lisofylline and related portfolio for development in diabetesProduct Licensing - Company inks licensing agreement in Mexico for Decapeptyl Depot, Decapeptyl LAProduct Licensing - HEALTHPOINT enters licensing agreement for two late-stage topical analgesicsProduct Licensing - License agreement for glioblastoma multiforme treatment candidate signedProduct Licensing - License rights for gene targeting technologies granted to Johnson & JohnsonProduct Licensing - Pharmaceutical companies finalize license agreement for common cold therapeuticProfessional Education - Former house speaker to present at health care congressProstate Cancer - Calcitriol induces prostate-derived factor expression in tumor cellsProstate Cancer - Company reaches milestone in development of prostate cancer classification testProstate Cancer - Experience with Vattikuti Institute prostatectomy reportedProstate Cancer - Interstitial microwave thermal therapy shows promiseProstate Cancer - Modified yeast assay improves detection of p53 abnormalities in prostate cancerProstate Cancer - More precise radiation therapy lets patients avoid erectile dysfunctionProstate Cancer - Researchers report on case of spinal cord metastasis from prostate cancerProstate Cancer - Retinol, lycopene not significantly related to prostate cancer risk in studyProtein Folding - Wild-type spectrin domains of the same stability vary kineticallyProtein Methylation - Stable HeLa cell protein methylation produced by adenosine dialdehyde treatmentProtein Structure - Predictive models for protein crystallization developedProteins - Heart, tooth germ, and kidney are sites of P-B expressionProteomics - Escherichia coli MntH studied, importance of acidic residues revealedProteomics - Activation and activity of protein kinase isoforms of a bivalve mollusk studiedProteomics - Application of mass spectrometry data to proteomics research describedProteomics - Bone morphogenetic proteins are secreted early during embryonic developmentProteomics - Desensitization of activated sphingosine-1-phosphate receptors revealedProteomics - Lipid activation of beta 2-chimaerin analyzed, structural mechanism revealedProteomics - Mediation of protein sorting to the mitochondrial intermembrane space revealedProteomics - Melanocortin receptor subtypes studied, preference to specific peptides revealedProteomics - Nonspecific interaction between cytochromes b(5) and P450 revealedProteomics - Novel peptide array enables efficient kinome analysisProteomics - Peptic cleavage of bovine beta-casein studied, peptides characterizedProteomics - Phospholipase C-epsilon studied, activation mechanism revealedProteomics - Photoperiod-regulated expression of gene encoding a CO/COL homolog studiedProteomics - Properties of mutant alpha-tropomyosin were compared to wild proteinProteomics - Protection techniques foster the construction of oligonucleotide constructsProteomics - Proteins with fullerol studied, detection by light scattering determinedProteomics - Rapid analysis of large protein-protein complexes using NMR developedProteomics - Real-time organelle analysis performed using surface plasmon resonanceProteomics - Reports advance knowledge in proteomics researchProteomics - Researchers report details of new studies and findings in the area of proteomicsProteomics - STA1 expression in yeast studied, role of Swi/Snf complex clarifiedProteomics - Scaffolding protein regulates NMDA channel gating and surface expressionProteomics - Shape changes in Arf1 linked to nucleotide exchange and loss of binding sitesProteomics - Structural basis of cellular redox regulation by human TRP14 describedProteomics - Study investigated determinants of PIP2 interaction with HERGProteomics - Zinc-finger protein TIS11b destabilizes angiogenic cytokinePseudomonas - MucA-mediated coordination of secretion in Pseudomonas investigatedPsoriatic Arthritis - U.S., European submissions made for HumiraPublic Health - Gangrene, pneumonia, and risk of malaria in some tsunami refugee campsPulmonary Hypertension - Results from STRIDE-4 releasedPulmonary Hypertension - U.S. FDA approves Ventavis for pulmonary arterial hypertensionPulmonary Hypertension - Vasoactive mediators from smoke exposure provoke pulmonary artery changesQuality Assurance - Consultants present long list of fixes for Los Angeles hospitalQuality Assurance - Methods may help in designing methods of quality control for interviewsQuality Assurance - Oregon nursing homes improve as a result of quality initiativeQuality Assurance - Vermont hospitals file new reports with state detailing services providedRNA Research - DNA and RNA surveillance are linked to mRNA exportRNA Research - Fourier transform infrared spectroscopy discerns RNA bulge structuresRNA Research - Mullerian duct analyzed, altered matrix metalloprotein mRNA expression revealedRNA Research - RNA polymerase II-dependent promoter derivatives expand the potential of siRNARabies - First rabies survivor without vaccination leaves hospitalRadiotherapy - Risk estimation made of hereditary effects due to radiation therapyReceptor Studies - Entrapment of membrane-bound receptors in silica reportedReceptor Studies - Opioid receptor blockade helps mice escape Fas-induced hepatitisReceptor Studies - Quantitative analysis of drug-protein binding conductedReceptor Studies - Toll-like receptors may be targets for treating chronic inflammatory diseasesReceptors - VPAC(1) receptors studied, inverse antagonism revealedRecombinant Research - Heat shock proteins used to produce recombinant proteins in E. coli Reconstructive Microsurgery - Peripheral nerve regeneration within nerve conduit characterizedRegulatory Issues - Discount health plans crackdown by state stops false and misleading advertisingRegulatory Issues - Treating individuals: How generalizable are trial data?Renal Cancer - Angiogenesis inhibitors help patients with advanced renal cell carcinomaRenal Cell Carcinoma - Use of retinoids in the treatment of renal cell carcinoma may be a futile effortRenal Disease - Chloride channel Kb gene mutations direct renal tube cell calcium handlingRenal Disease - Company partners with ADDNET consortiumRenal Disease - Kidney disease in Arima syndrome resembles disease in other disordersRenal Disease - Renal complications in Fabry disease associate with a unique gene variantReproductive Biology - Blocked and non-blocked 2-cell stage embryos are susceptible to culture effectsReproductive Biology - Changes in NO production cause uterine quiescence in pregnancy, start of laborReproductive Biology - Genetic selection of mouse male germline stem cells demonstratedReproductive Biology - Mechanism of VEGF-induced uterine venous hyperpermeability elucidatedRespiratory Medicine - Bronchoalveolar lavage fluid tests do not reflect pulmonary fibrinolysisRespiratory Medicine - Interferon benefits patients with recurrent respiratory papillomatosisRespiratory Medicine - Phase II trial initiated to study aerosolized antibiotic for pneumoniaRespiratory Medicine - Vitamin D receptor gene polymorphisms links to asthma and allergy studiedRetinopathy - Upregulated VEGF in RPE cells does not produce choroidal neovascularizationRheumatic Heart Disease - Mannose-binding lectin may cause complement activation that leads to RHDRheumatoid Arthritis - Long-term outcome of posterior-cruciate-retaining TKA clarifiedRhodopsin - Rhodopsin crystallized; native, altered and heavy atom forms studiedRhodopsin - Rhodopsin signaling and organization studied in knockout miceRibosomes - Small ribosomal subunit changes shape during translocationRounded Atelectasis - Researchers report on asbestos-exposed worker with rounded atelectasisSARS - An unusual RNA structure in the SARS virus offers a promising targetSARS - Assay for studying mutations of SARS virus protease developedSARS - Geographic information system offered real-time tracking of SARS spreadSARS - Polyprotein cleavage and chemical modification of SARS proteinase reportedSARS Coronavirus - Reports describe recent advances in SARS coronavirus researchSARS Prevention - Knowledge level regarding SARS transmission associated with formal educationSalla Disease - Mutations in transporter protein shed light on neurodegenerative diseasesSalmonella - B12 -adenosyl transferase encoded within Salmonella enterica operonSalmonella - Lack of YggX results in chronic oxidative stress in Salmonella Salpingitis - New bacterial phylotypes found in Fallopian-tube specimensSarcoidosis - North Carolina researchers look for link to disease behind White's deathScabies Diagnostics - Asymptomatic S. scabiei infestation revealed by serology of Caprinae hostsSexual & Reproductive Health - New drug application submitted for premature ejaculationSexual and Reproductive Health - Diet does not influence reproductive outcomes in mice lacking the Socs-2 geneSexual and Reproductive Health - Murine scans identify genes associated with oocyte maturationSexual and Reproductive Health - Primary follicles are stockpiled in polycystic ovary syndromeSkin Cancer - Melanocortin 1 receptor variants affect skin cancer susceptibilitySmall Bowel Transplantation - Nitric oxide production in epithelial cells is synergistically stimulatedSmallpox Vaccines - Recent findings in smallpox vaccines provide new insightsSmooth Muscle Cells - Epidermal growth factor receptor involved in vascular smooth muscle growthSocial Stress - During social stress, catecholamines play role in blood-leukocyte redistributionSociological Research - Report describes issues regarding the typology of maritally violent menSoft Tissue Sarcoma - Licensed oncology drug for soft tissue sarcoma in clinical trials at Wayne StateSpinal Cord Compression - Researchers report on vertebroplasty for tumor-related spinal cord compressionSpinal Cord Injury - BMTs provide tissue protection/axon guidance after contusive spinal cord injurySpinal Cord Injury - Federal grant to be used for cell therapy researchStaffing - Healthcare officials say man worked as nurse without licenseStaffing - Maker of contrast agent renews contract with Canadian UnionStaffing - Nursing shortage may be hurt by new State Department practiceState Medicaid - Florida Medicaid renews contract with HMS for revenue recovery servicesState Medicaid - Iowa Governor says raise cigarette tax to help fund MedicaidState Medicaid - Mississippi's top lawmaker worries Medicaid shortfall could growState Medicaid - New state Medicaid reform proposals released in New HampshireStatins - Consumers, pharmacists are more positive than doctors about OTC statinsStem Cell Research - CD19+/CD20+ cells efficiently separated via magnetic cell separation techniqueStem Cell Research - CXCR4 important for mediating specific migration of MSCs to bone marrowStem Cell Research - Criticism of new $3 billion California stem cell agency mountsStem Cell Research - Delayed TNF-alpha exposure increases yield of CD83+ dendritic cellsStem Cell Research - FGF6 role in maintenance of reserve pool of progenitor cells in skeletal muscleStem Cell Research - Hematopoietic stem cell expansion is a plausible clinical goalStem Cell Research - MMG disrupts collagen I/integrin signaling during osteoblastic differentiationStem Cell Research - Mesangioblasts transdifferentiate into satellite cells in myogenic environmentStem Cell Research - Mesenchymal progenitor cells are present in the umbilical cordStem Cell Research - Microfabricated platform studies stem cell fatesStem Cell Research - Non-muscle stem cells do not regenerate normal muscle tissueStem Cell Research - Nucleostemin plays important role in self-renewal of cancer cellsStem Cell Research - Oct4 required for primordial germ cell survivalStem Cell Research - Physical defect repair enhanced by implanting MSC cultured with TGF-beta 3Stem Cell Research - SKPs can be isolated from skin during embryogenesis and persist into adulthoodStem Cell Research - StemCells Inc. seeks trial of stem cells in Batten diseaseStem Cell Research - Trabecular bone fragment alternative source of mesenchymal stem cellsStem Cell Research - hEBs generated from ESC suspensions within 3D porous alginate scaffoldsStem Cell Transplantation - GVHD still a major limitation to successful hematopoietic SCTStem Cell Transplantation - HD radiochemotherapy followed by ASCT improves survival in follicular lymphomaStem Cell Transplantation - Non-myeloablative SCT safer than myeloablation for autoimmune diseasesStenosis - NT pro-BNP is a useful marker for evaluating aortic stenosisStents - Researchers prefer stenting for SA obstructive lesionsStents - Study evaluated effects of beta-irradiation for in-stent restenosisStress - Mothers in the workplace held to stricter standards, study suggestsStress - Study suggests women suffer more stress than men and handle it differentlyStress Induction - Multiple stress signals induce p73 beta accumulationStroke - HealthEast hospitals earn Joint Commission Primary Stroke Center CertificationStroke - Heavy drinking linked to higher stroke riskStroke - Ischemic stroke review provides data on hypertension and hyperlipidemiaStroke - Patients with essential hypertension form cerebral white matter lesionsStroke - Risk is greater for migraine sufferers, especially those on oral contraceptivesStroke - Specific gene variations may pose a risk for ischemic strokeSubstance Abuse - Australian group calls for revised guidelines on alcohol during pregnancySubstance Abuse - CDC grant enables research on alcohol-exposed pregnancies to continueSudden Infant Death Syndrome - Repeated unexpected infant deaths most likely to be from natural causesSurgical Devices - Guidewire can be useful tool in treatment of chronic total occlusionsSurgical Devices - Study assessed patient tolerance and utility of using closure deviceSurgical Technology - Adipose-derived stem cells for repairing human skull defects reportedSurgical Technology - Axial femorotibial rotation after TKA characterizedSurgical Technology - Carter-Thomason CloseSure System XL launches in the United StatesSurgical Technology - Collegium announces licensing agreement for two late-stage productsSurgical Technology - Company reports first major peer-reviewed clinical article on PARSUS technologySurgical Technology - Conference to highlight developments in cosmetic surgerySurgical Technology - Evolution of robotic urologic surgery reviewedSurgical Technology - FDA issues 510(k) clearance for CardioPAT surgical blood salvage systemSurgical Technology - High-flexion knee arthroplasty design replicates healthy motionSurgical Technology - Image-based computer-assisted TKA has lower coronal alignment variabilitySurgical Technology - Imaging center announces noninvasive procedure for uterine fibroidsSurgical Technology - Long-term efficacy of unicompartmental knee replacement determinedSurgical Technology - Morselized bone grafts stabilize cementless acetabular revisionsSurgical Technology - Outcome of different TKA configurations evaluatedSurgical Technology - Percutaneous treatment of renal artery stenosis effective in childrenSurgical Technology - Polyethylene bearing mobility preserved in posterior stabilized TKASurgical Technology - Report looks at European market for bone morphogenic proteins in spine fusionSurgical Technology - Report published examining forecast in eight major surgical specialtiesSurgical Technology - TVAC is a promising device to protect microcirculation in reperfusionSystemic Lupus Erythematosus - U.S. FDA grants epratuzumab Fast Track Product designationTangier Disease - Cassette transporter A1 requires a specific motif for several activitiesTelemedicine - International Space Station uses telemedicine technologyThrombin - Lung barrier function studied, differential thrombin regulation revealedThyroid Hormone - Na, K-ATPase activity and expression studied, role of two kinases revealedTobacco Use - American Lung Association gives Oregon poor gradesTobacco Use - Nicotine increases blood-brain barrier permeability in vivoToxicology - Cell sorting techniques are not genotoxic to spermatozoaToxicology - Method for in vivo bioluminescent monitoring of toxicity developedToxicology - Synthesized compounds immobilize cadmium or lead toxinsToxicology - Tool to study oxidative stress and inhalation toxicokinetics developedTranscription Factors - R-dependent transcription factor activity studied, different mechanisms revealedTransfection - Researchers detail new studies and findings in the area of transfectionTransitional Cell Carcinoma - Researchers report on transitional cell carcinoma in renal transplant recipientsTransplant Medicine - Donor-derived, alloreactive natural killer cells may interfere with immunityTransplant Medicine - Researchers provide details of new studies and findings in the area of transplant medicineTrichomonas vaginalis - T. vaginalis inhibits proinflammatory cytokines via NF-kappa B supressionTrypanosoma - Plant arginine decarboxylase gene expressed in Trypanosoma cruzi Tuberculosis - Companies sign agreement to assess potential of tuberculosis testing technologyTuberculosis - Concepts of gender, culture, and TB explored among uninfected Indian populationTuberculosis - Woman died of tuberculosis in November, health officials sayTuberculosis Diagnosis - Simple sputum test useful to confirm childhood tuberculosisTumor Suppression - Cdk inhibitor p21 has tumor suppressor function in colonType 1 Diabetes - Intracellular stress signaling pathways activated during islet preparationType 1 Diabetes - Sources for new pancreatic beta cells in adult life outlinedType 1 Diabetes Screening - Simple test for autoantibodies to glutamic acid decarboxylase developedType 2 Diabetes - 7-Hydroxystaurosporine inhibits Akt Thr308 ) not Ser473 phosphorylationType 2 Diabetes - Hepatic production of VLDL1 but not VLDL2 related to insulin resistanceType 2 Diabetes - Stage-matched intervention promotes exercise in patients with type 2 diabetesUlcerative Colitis - Management of postoperative pouchitis reviewedUrinary Tract Infections - Drug-resistant UTI outbreak likely caused by contaminated foodUrogenital Research - Feline urogenital junction studied, morphology and innervation pattern reportedUrology - Pelvic floor reconstruction reviewedUterine Fibroids - Interim assessment of 1-month data from uterine fibroid therapy releasedVaccine Development - Dendritic cell expansion potentiates the immunogenicity of plasmid DNA vaccineVaginal Infection - Mannose binding lectin and C3 act as recognition molecules for pathogensViral Genomics - Findings advance knowledge in viral genomics researchVirology - Aromatic cations eradicate viral infection in cells destined for cloningVirology - DNA aptamer prevents influenza infectionVirology - New research in the area of virology detailedVirology - Post-transcriptional RNA processing characterized in HSV-infected cellsVirology - Researchers' data advance virology researchWilson Disease - Copper metabolism in Wilson disease clarified using proteomic analysisWound Care - Ethylene oxide is best method to sterilize chitosan wound dressingsWound Care - Hydrogels as wound-dressing materials investigatedYellow Fever - Risk of yellow fever emergence predicted for Rio de JaneiroZoonoses - Novel immunoassay suitable for diagnosis of porcine Nipah virus infectionvon Willebrand Disease - Novel von Willebrand factor mutation causes skipping of nonadjacent exons
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