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Adenovirus



Antihexon antibody model neutralizes adenovirus



January 25th, 2005

An antihexon antibody model neutralizes adenovirus.

According to a study from the United States, "Antibodies against hexon, the major coat protein of adenovirus, (Ad), are an important component of the neutralizing activity in serum from naturally infected humans and experimentally infected animals.

"The mechanisms by which antihexon antibodies neutralize the virus have not been defined. As a model system, murine monoclonal antibodies raised against Ad type 5 (Ad5) were screened for antihexon binding and neutralization activity; one monoclonal antibody, designated 9Cl2, was selected for further characterization."

"The minimum...


Source: Life Science Weekly (2005-01-25)

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