Life Science Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Life Science Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Adult T-Cell Leukemia
Adult T-cell leukemia cells down-regulate CD26 antigens via epigenetic machinery
January 25th, 2005
Adult T-cell leukemia cells down-regulate CD26 antigens via epigenetic machinery. According to published research from Japan, "CD26/dipeptidyl peptidase IV (DPPIV), a T-cell-activation antigen, is a 110-kD type II surface glycoprotein expressed on various types of normal cells. CD26/DPPIV is considered a multifunction housekeeping protein. Malignant cells often show altered CD26/DPPIV expression or no CD26/DPPIV expression, thus suggesting a useful marker for assessing some T-cell malignancies. "In this study, cell surface protein and messenger RNA expression profiles for CD26/DPPIV were examined in 49 patients with adult T-cell leukemia (ATL), 10...
Source: Life Science Weekly (2005-01-25)
|
