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Alcohol Use



Taurine not involved in pharmacological effects of ethanol in rats



January 25th, 2005

Taurine is not involved in the pharmacological effects of ethanol in rats.

"Recent microdialysis studies showed that ethanol administration increases the release of taurine in various rat brain regions, and it was suggested that this increase in extracellular concentrations of taurine might mediate some of the neurochemical effects of ethanol," scientists in North Carolina explained. "Previous drug discrimination studies showed that positive modulators of the GABAA receptor consistently substituted for ethanol discriminative stimulus effects."

"Since taurine is also believed to modulate GABAA receptor activity," E. Quertemont...


Source: Life Science Weekly (2005-01-25)

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