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Angiology
Mef2c mediates vascular gene expression during endothelial cell development
January 25th, 2005
Mef2c mediates vascular gene expression during endothelial cell development. "Members of the myocyte enhancer factor 2 (MEF2) family of transcription factors play key roles in the development and differentiation of numerous cell types during mammalian development, including the vascular endothelium. Mef2c is expressed very early in the development of the endothelium, and genetic studies in mice have demonstrated that mef2c is required for vascular development. However, the transcriptional pathways involving MEF2C during endothelial cell development have not been defined," scientists in the United States report. "As a first step towards identifying...
Source: Life Science Weekly (2005-01-25)
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