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Proteolysis
Xenopus laevis egg envelope hardening studied, role of proteolysis revealed
January 25th, 2005
Researchers from the united States have reported that proteolysis of a Xenopus laevis egg envelope glycoprotein triggers envelope hardening. "The egg envelope of most animal eggs is modified following fertilization, resulting in the prevention of polyspermy and hardening of the egg envelope. In frogs and mammals a prominent feature of envelope modification is N-terminal proteolysis of the envelope glycoprotein ZPA. "We have purified the ZPA protease from Xenopus laevis eggs and characterized it as a zinc metalloprotease," wrote L.L. Lindsay and colleagues, University of California, Davis. "Proteolysis of isolated egg...
Source: Life Science Weekly (2005-01-25)
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