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Cardiology



Novel therapy for lipid disorders shows mixed results in early clinical trials



April 10th, 2007

Preliminary research suggests that use of a novel, potent drug to treat cholesterol disorders decreases triglycerides and increases HDL-C, the "good" cholesterol, but also raises some safety concerns, according to a study in JAMA. The study was released to coincide with its presentation at the American College of Cardiology's annual conference.

Several different classes of drugs are used to treat lipid disorders. Fibrates reduce the liver's production of a triglyceride-carrying particle and speed up removal of triglycerides from the blood. Statins reduce cholesterol levels by inhibiting an enzyme that produces cholesterol in the liver. New, more potent and selective...


Source: Life Science Weekly (2007-04-10)

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