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Life Science Weekly

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Dentistry



Study describes action of estrogen in protecting bone



April 10th, 2007

Researchers at the University at Buffalo have described a novel pathway by which estradiol, the primary estrogen in humans, aids in maintaining bone density, a function critical to avoiding osteoporosis.

It is well known that estrogen is essential for healthy bone, and that when the production of estrogen is reduced, as occurs normally in postmenopausal women and pathogenically after exposure to radiation or chemotherapeutic drugs, bones become brittle and break easily. However, the mechanisms involved aren’t clearly understood.

The new study found that one way estradiol helps to maintain bone density is by stopping the activation of an enzyme known...


Source: Life Science Weekly (2007-04-10)

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