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Genetics & Genomics
Gladstone scientists identify critical gene factor in heart development
April 10th, 2007
Researchers at the Gladstone Institute of Cardiovascular Disease (GICD) announced they have identified a critical genetic factor in the control of many aspects of heart form and function. As reported in the journal Cell, scientists in the lab of Deepak Srivastava, MD, have successfully deleted a genetic factor, called a microRNA, in animal models to understand the role it plays in cardiovascular differentiation and development. MicroRNAS, or miRNAs, seem to act as rheostats or "dimmer switches" to fine-tune levels of important proteins in cells. To learn how microRNAs do this, the team led by Dr. Srivastava, deleted the gene responsible for one microRNA in mice and...
Source: Life Science Weekly (2007-04-10)
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