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Life Science Weekly

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Osteoporosis



Scientists identify a candidate gene for osteoporosis



April 10th, 2007

Researchers have reported the identification of a gene that may play a role in susceptibility to osteoporosis—the crippling disease that leads to bone fractures, especially of the hip and spine. The study, conducted by scientists at the Musculoskeletal Diseases Center of the Jerry L Pettis Memorial Veteran's Affairs Medical Center at Loma Linda, shows convincing evidence that a gene called DARC negatively regulates bone density in mice. The report appears online in Genome Research.

"If our finding using the mouse model is confirmed in humans, then we may be able to develop therapies that are based on inhibiting the function of the DARC gene," explains Dr. Subburaman...


Source: Life Science Weekly (2007-04-10)

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