Dental Enamel Proteins
Research from National Institutes of Health in the Area of Dental Enamel Proteins Published
Published in Life Science Weekly, February 28th, 2012
2012 FEB 28 -- According to the authors of recent research published in the European Journal of Oral Sciences, "The amelogenin proteins are required for normal enamel development, and the most abundant amelogenins expressed from alternatively spliced mRNAs are M180 and leucine-rich amelogenin protein (LRAP). The X-Chromosomal Amelogenin (Amelx) null [knockout (KO)] mouse has an enamel defect similar to human X-linked amelogenesis imperfecta."
"The disorganized enamel layer in KO mice is 10-20% of the thickness of wild-type (WT) enamel and lacks prismatic structures. When the KO mice were mated with mice that express the transgene M180-87, (TgM180-87)...
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Source: Life Science Weekly (2012-02-28)
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