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Research from University of Oxford Yields New Data on Life Science

Published in Life Science Weekly, March 13th, 2012

2012 MAR 13 -- Researchers detail in "Paternal age effect mutations and selfish spermatogonial selection: causes and consequences for human disease," new data in Life Science. According to the authors of recent research from Oxford, United Kingdom, "Advanced paternal age has been associated with an increased risk for spontaneous congenital disorders and common complex diseases (such as some cancers, schizophrenia, and autism), but the mechanisms that mediate this effect have been poorly understood. A small group of disorders, including Apert syndrome (caused by FGFR2 mutations), achondroplasia, and thanatophoric dysplasia (FGFR3), and Costello syndrome (HRAS), which we...

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