Schizophrenia

Findings from McGill University in Schizophrenia Reported

Published in Life Science Weekly, April 10th, 2012

2012 APR 10 -- "Epidemiological evidence suggests that maternal infection during pregnancy may be a risk factor for schizophrenia and autism. Altered expression of glutamic acid decarboxylase (GAD67) and reelin in the hippocampus has been reported in post-mortem studies of people with schizophrenia or autism," investigators in Verdun, Canada report.

"We used two mouse models of maternal inflammation, featuring either the viral RNA mimic, poly (I:C), or the bacterial endotoxin, lipopolysaccharide (LPS), to compare effects of maternal inflammation on GAD67 and reelin expression in the hippocampal stratum oriens of juvenile mice. Pregnant Swiss-Webster mice...

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Source: Life Science Weekly (2012-04-10)

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