Hospital Necker Enfants Maladies, Paris
Host T cell expansion in FHLH patients occurs early after HSCT in a setting of a viral infection
Published in MD Week, December 16th, 2005
"Familial hemophagocytic lymphohistiocytosis (FHLH) is a genetic disorder caused by defective lymphocyte cytotoxicity, resulting in impaired lymphocyte homeostasis and macrophage infiltration of solid tissues and bone marrow, with extensive hemophagocytosis. It is invariably fatal unless treated by allogeneic hematopoietic stem cell transplantation (HSCT)," scientists in France report.
According to the investigators, "In a retrospective analysis of 11 cases of FHLH, transplanted in one...
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Source: MD Week (2005-12-16)
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