Breast Cancer
Scientists from University of California, U.S., target breast cancer
Published in MD Week, November 24th, 2006
Study 1: 15-hydroxyprostaglandin dehydrogenase (15-PGDH) might be a tumor suppressor gene in breast cancer.
According to a study from the United States, "Prostaglandin E-2 plays a growth-stimulatory role in breast cancer, and the rate-limiting enzyme in its synthesis, cyclooxygenase-2, is often overexpressed in these cancers. Little is known about the role of the key prostaglandin catabolic enzyme 15-PGDH in breast cancer pathogenesis."
"Using a pharmacologically based screen for epigenetically silenced genes, we found low levels of...
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Source: MD Week (2006-11-24)
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