Published in MD Week, September 7th, 2007
Normally males have one X and one Y chromosome and females have two X chromosomes. But Postdoctoral Research Officer Dr Edwina Sutton has produced male mice with two X chromosomes by artificially activating a gene in the developing gonads.
“The gene – Sox3 on the X chromosome – is well known for its impact on brain development, but this is the first time it’s ever been shown to change sexual development. By making this brain gene active in the developing gonads of mice with two X chromosomes...
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