Malaria Vaccines

Use of Two Antigens May Be Beneficial

Published in Malaria Weekly, February 5th, 1996

The inclusion of two antigens in a malaria transmission-blocking vaccine may increase the proportion of people who respond to the immunogen.

Malaria transmission-blocking vaccines may be of use in numerous control or quarantine modalities, noted E.A. Ohas, U.S. Army Medical Research Unit, Kenya, and colleagues ("Cellular and Humoral Recognition of Candidate Malaria Transmission-Blocking Vaccine Antigens in Naturally Exposed Persons," American Journal of Tropical Medicine and Hygiene, abstract 147, 1995;53(2):137).

Two Plasmodium falciparum surface proteins (Pfs25 and Pfs28) materialize as the malaria parasite develops in the midgut of the...

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Source: Malaria Weekly (1996-02-05)

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