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Parasitology

"Origins of the Parasitophorous Vacuole Membrane of the Malaria Parasite: Surface Area of the Parasitized Red Cell."

Published in Malaria Weekly, February 5th, 1996

According to the authors' abstract of an article published in European Journal of Cell Biology, "There is conflicting evidence on whether the parasitophorous vacuole membrane, in which the malaria parasite becomes encapsulated when it enters the red cell, represents a part of the host cell membrane or is derived, at least in part, from the parasite. We have measured the surface area of populations of red cells before and after invasion by up to four merozoites of the malaria parasite, Plasmodium falciparum. The dimensions of the merozoite are such that, if it enveloped itself entirely in host cell membrane during entry, the loss of surface area would amount to some 4...

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