Published in Malaria Weekly, November 28th, 2005
"Human erythrocyte membranes express the multidrug resistance-associated proteins, MRPI, MRP4 and 5, that collectively can efflux oxidized glutathione, glutathione conjugates and cyclic nucleotides. It is already known that the quinoline derivative, MK-571, is a potent inhibitor of MRP-mediated transport.
"We here examine whether the quinoline-based antimalarial drugs, amodiaquine,...
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